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MC-Gly-Gly-Phe-Boc

  CAS No.: 1599440-14-8   Cat No.: BADC-01706 4.5  

MC-Gly-Gly-Phe-Boc is a peptide-based ADC linker intermediate with enzyme-cleavable sequence and Boc protection, facilitating controlled payload release in antibody-drug conjugates. Keywords: ADC linker, peptide linker, enzyme-cleavable, Boc protection, controlled release.

MC-Gly-Gly-Phe-Boc

Structure of 1599440-14-8

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ADC Linker
Molecular Formula
C27H36N4O7
Molecular Weight
528.60

* For research and manufacturing use only. We do not sell to patients.

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Popular Publications Citing BOC Sciences Products
Synonyms
L-Phenylalanine, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-, 1,1-dimethylethyl ester
Density
1.218±0.06 g/cm3
Boiling Point
820.2±65.0 °C at 760 mmHg

MC-Gly-Gly-Phe-Boc, a versatile chemical compound, is widely utilized across diverse fields, notably in peptide synthesis and research. Here are four key applications of MC-Gly-Gly-Phe-Boc:

Peptide Synthesis: Serving as a fundamental building block in solid-phase peptide synthesis, MC-Gly-Gly-Phe-Boc plays a pivotal role. Its protected form acts as a safeguard, preventing premature reactions of specific functional groups during synthesis. This meticulous approach facilitates the efficient and precise assembly of peptides, which are indispensable for the development of therapeutic drugs, vaccines, and biologics.

Bioconjugation Studies: Delving into bioconjugation research, MC-Gly-Gly-Phe-Boc is harnessed to craft peptide conjugates capable of attachment to biomolecules or surfaces. This innovative technique enables the exploration of protein interactions, cellular processes, and the design of diagnostic assays. The controlled and selective coupling offered by this compound aids in targeted research endeavors, elevating the possibilities within the field.

Pharmaceutical Research: At the forefront of pharmaceutical exploration, MC-Gly-Gly-Phe-Boc is instrumental in synthesizing novel peptide-based drug candidates. Researchers leverage this compound to delve into the structures and functions of peptides with therapeutic potential. Through the modification and optimization of these peptides, new treatments for a spectrum of ailments, including cancer and infectious diseases, come into the realm of possibility.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: MC-Gly-Gly-Phe | Boc-Ser(O-propargyl)-OH | m-PEG2-NHS ester | MC-Gly-Gly-Phe-Boc
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