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Drugs are complex molecules that can undergo chemical changes over time due to various factors, such as temperature, humidity, light, and pH. These changes can affect the potency, safety, and efficacy of drugs, and may lead to adverse reactions or reduced therapeutic benefits. To preserve their quality and shelf life, medications must therefore undergo stability analysis. The experienced team of analytical experts from BOC Sciences ensures the quality and shelf life of ADC drugs using the latest cutting-edge equipment and technology. We take a highly customized approach to our ADC stability analysis services. We understand that each project is unique, and thus, tailor our service to meet the exact needs of our clients. With a focus on accuracy and reliability, our team leaves no stone unturned when it comes to the stability analysis of drugs.
Antibody-drug conjugates (ADCs) are a groundbreaking class of therapeutic agents that amalgamate the specificity of monoclonal antibodies with the cytotoxicity of small-molecule drugs, representing a game-changing approach in the fight against diseases like cancer. However, their development and optimization is not without its challenges, as factors such as conjugation chemistry, linker stability, and drug release kinetics can all have a significant impact on their stability and efficacy. This is where the stability analysis of ADCs plays a pivotal role, serving as a critical component in ensuring their safety and effectiveness. At BOC Sciences, we recognize the importance of conducting thorough and comprehensive stability analysis of ADCs to ensure that they meet the highest standards of safety and efficacy. Our team of experts is highly experienced in the latest analytical techniques and state-of-the-art equipment, allowing us to deliver highly accurate and reliable results every time. By taking a proactive and highly customizable approach to stability analysis, we help our clients achieve their goals with confidence and peace of mind, staying one step ahead of the competition in the process.
Fig. 1. Antibody-drug conjugate general mechanism-of-action (Chem. Soc. Rev., 2022, 51, 3886-3897).
BOC Sciences is an organization that is committed to delivering top-tier drug development and analytical services, which encompass an extensive suite of comprehensive ADC stability analysis procedures. Our team comprises of highly experienced and knowledgeable scientists and analytical experts who are well-versed in the implementation of an impressive array of cutting-edge tests and assays that are utilized to meticulously evaluate the stability and performance of ADCs. Our approach entails an exhaustive consideration of every element that constitutes an ADC, including but not limited to, the antibody, linker, and drug. Our focus on the highest standards of quality and consistency ensures that our clients' ADCs are thoroughly scrutinized and meet the most stringent benchmarks for excellence.
BOC Sciences' ADC stability analysis service is tailored to meet the specific needs of each client. Our company can customize the service to include additional tests and assays as required.
BOC Sciences' ADC stability analysis service is conducted by a team of experienced scientists and analytical experts who have extensive knowledge and expertise in the field of ADC development and analysis.
BOC Sciences uses state-of-the-art equipment and techniques to ensure accurate and reliable results. The company's equipment includes HPLC, MS, and other analytical instruments.
BOC Sciences is a highly specialized and proficient provider of comprehensive ADC characterization services. Our team of experts meticulously analyzes every aspect of antibodies, drugs, linkers, and conjugation chemistries to ensure the quality and consistency of ADCs. In addition, we offer an all-encompassing suite of services to measure the ADME of ADCs in vivo, leveraging a wide range of animal models or other pharmacokinetic assays to effectively assess their pharmacokinetic profile and therapeutic potential. We take great pride in our ability to provide a full spectrum of ADC development services, including design and synthesis, characterization, stability analysis, and pharmacokinetic and toxicological testing. At BOC Sciences, we employ state-of-the-art equipment and cutting-edge methodologies to provide our clients with the highest level of service and support throughout the entire ADC development process.
