MC-Gly-Gly-Phe-Gly - CAS 2413428-36-9
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MC-Gly-Gly-Phe-Gly - CAS 2413428-36-9 Catalog number: BADC-01108

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MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
MC-Gly-Gly-Phe-Gly
CAS
2413428-36-9
Catalog Number
BADC-01108
Molecular Formula
C25H31N5O8
Molecular Weight
529.54
Purity
>98.0%

Ordering Information

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BADC-01108 -- $-- Inquiry

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Description
MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
Synonyms
(S)-5-Benzyl-18-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazaoctadecan-1-oic acid
IUPAC Name
2-[[(2S)-2-[[2-[[2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]acetic acid
Canonical SMILES
C1=CC=C(C=C1)CC(C(=O)NCC(=O)O)NC(=O)CNC(=O)CNC(=O)CCCCCN2C(=O)C=CC2=O
InChI
InChI=1S/C25H31N5O8/c31-19(9-5-2-6-12-30-22(34)10-11-23(30)35)26-14-20(32)27-15-21(33)29-18(25(38)28-16-24(36)37)13-17-7-3-1-4-8-17/h1,3-4,7-8,10-11,18H,2,5-6,9,12-16H2,(H,26,31)(H,27,32)(H,28,38)(H,29,33)(H,36,37)/t18-/m0/s1
InChIKey
DWPLKZYCOGLRPC-SFHVURJKSA-N
Sequence
MC-Gly-Gly-Phe-Gly
Density
1.331±0.06 g/cm3(Predicted)
Solubility
10 mm in DMSO
Appearance
Solid Powder
Shelf Life
-20°C 3 years powder; -80°C 2 years in solvent
Shipping
Room temperature
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Boiling Point
1009.8±65.0°C(Predicted)
Form
Solid
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Calculate
The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Calculate

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Historical Records: (2-pyridyldithio)-PEG4 acid | Me-Tet-PEG4-Maleimide | BCN-PEG1-Val-Cit-OH | Gly-NH-CH2-Boc | MC-Gly-Gly-Phe-Gly
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