2,5-dioxopyrrolidin-1-yl 3-(4-hydroxyphenoxy)propanoate is a linker for antibody-drug-conjugation (ADC).
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2,5-dioxopyrrolidin-1-yl 3-(4-hydroxyphenoxy)propanoate, a versatile organic compound with diverse applications in biotechnology and medicinal chemistry. Here are four key applications with a high degree of perplexity and burstiness:
Protein Labeling: Acting as a reagent for protein labeling, this compound facilitates the exploration of protein interactions, localization, and function. By binding to specific amino acid residues, it assists researchers in tracing proteins within cells or tissues. This method enhances comprehension of various biological processes and disease mechanisms.
Drug Delivery Systems: This compound plays a pivotal role in developing sophisticated drug delivery systems. Serving as a linker or carrier molecule, it can conjugate with drugs to enhance their stability and bioavailability. This strategy is paramount for precise drug delivery, elevating the therapeutic effectiveness of pharmaceuticals.
Polymer Synthesis: Serving as an intermediary for specialized polymer synthesis, this compound contributes to various biomedical applications. Polymers incorporating this molecule showcase unique characteristics such as biocompatibility and controlled degradation rates. These attributes are advantageous in crafting medical devices, tissue engineering scaffolds, and formulations for controlled release.
Chemical Biology: In the realm of chemical biology, researchers leverage this compound to investigate enzyme activities and protein functions. By forming covalent bonds with enzyme active sites, it aids in identifying and characterizing enzymatic pathways. This knowledge is indispensable for drug discovery and comprehending metabolic processes.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.