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CAS No.: 1134280-63-9
Cat No.: BADC-00520
4.5 
2,5-Dioxopyrrolidin-1-yl 3-(benzyloxy)propanoate is an NHS ester ADC linker facilitating conjugation via hydroxyl groups. The benzyloxy moiety enhances hydrophobic interactions, improving payload stability in antibody-drug conjugates.
Structure of 1134280-63-9
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2,5-Dioxopyrrolidin-1-yl 3-(benzyloxy)propanoate is a versatile chemical compound with diverse applications in biochemical research and pharmaceutical development. Here are four key applications described with high perplexity and burstiness:
Chemical Synthesis: Employed as a pivotal building block in organic synthesis, 2,5-Dioxopyrrolidin-1-yl 3-(benzyloxy)propanoate plays a crucial role in crafting intricate molecules. Its distinct structure facilitates the formation of peptide bonds, making it invaluable in synthesizing peptides and proteins. This compound streamlines synthetic pathways, simplifying complexities and boosting the efficiency of chemical reactions.
Drug Development: Positioned at the forefront of pharmacological innovation, this compound serves as a crucial intermediate in synthesizing biologically active molecules. It integrates seamlessly into drug discovery pipelines, fostering the creation of novel therapeutic agents with enhanced efficacy and safety profiles. Researchers leverage 2,5-Dioxopyrrolidin-1-yl 3-(benzyloxy)propanoate to explore new avenues and optimize the pharmacokinetic properties of potential drug candidates.
Proteomics: Within the realm of proteomics, this compound is pivotal for modifying and labeling proteins. By binding to specific amino acid residues, it facilitates in-depth investigations into protein structure, function, and interactions. This application is fundamental in pinpointing biomarkers, dissecting disease mechanisms, and crafting innovative diagnostic tools.
Bioconjugation: Embedded in bioconjugation methodologies, 2,5-Dioxopyrrolidin-1-yl 3-(benzyloxy)propanoate acts as a catalyst in linking biomolecules like antibodies, peptides, or nucleic acids to diverse surfaces or other molecules. This cutting-edge technology is indispensable for developing sophisticated biosensors, targeted drug delivery systems, and diagnostic assays. The precise conjugation it enables heightens the specificity and performance of these biotechnological applications.
2,5-Dioxopyrrolidin-1-yl 3-(benzyloxy)propanoate
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2,5-Dioxopyrrolidin-1-yl 3-(benzyloxy)propanoate
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