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2,5-Dioxopyrrolidin-1-yl 3-((2,4-Difluorobenzyl)oxy)propanoate

CAS No.: 1134280-65-1

Cat No.: BADC-00522 4.5

2,5-Dioxopyrrolidin-1-yl 3-((2,4-Difluorobenzyl)oxy)propanoate is a fluorinated NHS ester ADC linker promoting selective antibody conjugation and enhanced metabolic stability for improved antibody-drug conjugate performance.

2,5-Dioxopyrrolidin-1-yl 3-((2,4-Difluorobenzyl)oxy)propanoate

Structure of 1134280-65-1

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ADC Linker

Molecular Formula

C14H13F2NO5

Molecular Weight

313.25

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Canonical SMILES

C1CC(=O)N(C1=O)OC(=O)CCOCC2=C(C=C(C=C2)F)F

InChI

InChI=1S/C14H13F2NO5/c15-10-2-1-9(11(16)7-10)8-21-6-5-14(20)22-17-12(18)3-4-13(17)19/h1-2,7H,3-6,8H2

InChIKey

GVIIHBCHKKZQIM-UHFFFAOYSA-N

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Catalog	Product Name	CAS	Inquiry
BADC-00428	2,5-dioxopyrrolidin-1-yl 3-(2-(2-undec-10-ynamidoethoxy)ethoxy)propanoate	1006592-59-1
BADC-00515	2,5-Dioxopyrrolidin-1-yl 2,5,7,10-Tetraoxatridecan-13-Oate	1053657-02-5
BADC-00486	2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate	107348-47-0
BADC-00520	2,5-Dioxopyrrolidin-1-yl 3-(benzyloxy)propanoate	1134280-63-9
BADC-00521	2,5-Dioxopyrrolidin-1-yl 3-((2-Fluorobenzyl)oxy)propanoate	1134280-64-0
BADC-00526	2,5-Dioxopyrrolidin-1-yl 4-((2-(1,3-Dioxoisoindolin-2-Yl)ethyl)disulfanyl)butanoate	1190203-91-8
BADC-00476	2,5-dioxopyrrolidin-1-yl 2-(dimethylamino)-4-(pyridin-2-yldisulfanyl)butanoate	1193111-73-7
BADC-00527	2,5-Dioxopyrrolidin-1-yl 3-(4-Methoxyphenoxy)propanoate	1199815-10-5
BADC-00429	2,5-dioxopyrrolidin-1-yl 7,10,13-trioxa-4-azahexadec-1-yn-16-oate	1214319-94-4
BADC-00528	2,5-Dioxopyrrolidin-1-yl 4-((2-((2-(2-(4-(2,6-Dioxo-1,3-Dipropyl-2,3,6,9-Tetrahydro-1H-Purin-8-Yl)phenoxy)acetamido)ethyl)amino)ethyl)disulfanyl)-4-Oxobutanoate	1222787-24-7

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Historical Records: 2,5-dioxopyrrolidin-1-yl 18-((4-(3,5-dioxohexyl)phenyl)amino)-14,18-dioxo-4,7,10-trioxa-13-azaoctadecan-1-oate | Acid-PEG3-SS-PEG3-acid | IgG1-VcMMAE | 4-Formyl-N-(2-(2-Methoxy-4-Methylphenoxy)ethyl)benzamide | Seco-Duocarmycin MA | CHO-Ph-CONH-PEG3-NHS ester | Methyltetrazine-PEG4-oxyamine | sulfo-LC-SPDP | N-Boc-N-bis(PEG4-OH) | 2,5-dioxopyrrolidin-1-yl 3-(2-(2-undec-10-ynamidoethoxy)ethoxy)propanoate | 2,5-Dioxopyrrolidin-1-yl 3-((2,4-Difluorobenzyl)oxy)propanoate

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