Bis-PEG3-NHS Ester is used in ADC construction for efficient crosslinking of proteins via primary amines. Its PEG3 spacer enhances solubility, reduces immunogenicity, and enables controlled drug loading on antibodies.
Structure of 1314378-16-9
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Capabilities & Facilities
Bis-PEG3-NHS Ester, a versatile bifunctional crosslinker, finds extensive use in biological and biomedical research. Explore its diverse applications presented with elevated perplexity and burstiness:
Protein Crosslinking: This compound serves as a cornerstone in bioconjugation experiments, facilitating the covalent linkage of proteins and peptides. Through interactions with primary amines on lysine residues, it forges stable amide bonds, enabling the formation of intricate protein complexes. This method is indispensable for investigating protein-protein interactions and constructing multifunctional protein architectures, propelling the frontiers of protein research.
Surface Modification of Biomaterials: In the realm of biomaterials, Bis-PEG3-NHS Ester plays a pivotal role in surface functionalization, empowering researchers to graft desired molecules onto biomaterial surfaces. By affixing bioactive ligands, scientists can augment cell adhesion, proliferation, and differentiation, revolutionizing applications in tissue engineering and the advancement of cutting-edge medical implants.
Drug Delivery Systems: Embracing innovation, this crosslinker is harnessed to revamp drug delivery systems, including nanoparticles and liposomes, enhancing their targeting precision and therapeutic efficacy. By coupling targeting moieties like antibodies or peptides, drug carriers are tailored for enhanced delivery to specific tissues or cells, heralding a new era of targeted therapeutics with heightened potency and reduced adverse effects.
Diagnostic Assays: In the diagnostic landscape, Bis-PEG3-NHS Ester emerges as a key player, enabling the linkage of antibodies or antigens to detection systems with finesse. By conjugating these biomolecules to labels such as enzymes or fluorophores, researchers craft sensitive and specific diagnostic assays with unparalleled precision. This technique underpins the development of ELISAs and other immunoassays, revolutionizing disease detection and monitoring with unparalleled accuracy.
Catalog | Product Name | CAS | Inquiry |
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BADC-00379 | Bis-PEG4-NHS ester | 1314378-11-4 | |
BADC-00924 | Bis-PEG7-NHS ester | 1334170-02-3 | |
BADC-00960 | Bis-PEG6-NHS ester | 1526718-98-8 | |
BADC-01080 | Bis-PEG17-NHS ester | 2221948-93-0 | |
BADC-01081 | Bis-PEG25-NHS ester | 2221948-96-3 | |
BADC-01082 | Bis-PEG21-NHS ester | 2221948-98-5 | |
BADC-01083 | Bis-PEG13-NHS ester | 2221949-00-2 | |
BADC-01084 | Bis-PEG10-NHS ester | 2221949-02-4 | |
BADC-00381 | Bis-PEG2-NHS Ester | 65869-63-8 | |
BADC-00382 | Bis-PEG1-NHS ester | 65869-64-9 |
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