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Fmoc-Val-Ala-OH is a widely used cleavable peptide linker that can conveniently serve as a building block for the careful construction of peptide-directed therapeutics and pharmaceuticals. Its multifaceted nature holds great promise in combating a range of diseases, including but not limited to neoplastic diseases, autoimmune diseases, and potential infections.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01482 | 500 mg | $298 | Inquiry |
Fmoc-Val-Ala-OH, also known as N-[(9-Fluorenylmethoxycarbonyl)-L-valyl]-L-alanine, is a protected dipeptide utilized in peptide synthesis and biochemical research. Here are four key applications of this compound:
Peptide Synthesis: Serving as a cornerstone in solid-phase peptide synthesis (SPPS), Fmoc-Val-Ala-OH plays a pivotal role in crafting precise peptide sequences. Its Fmoc protective group enables methodical deprotection steps, ensuring the meticulous assembly of peptides. This dipeptide is essential for constructing intricate peptides utilized in pharmaceutical research and diagnostics, contributing to advancements in therapeutic development.
Protein Engineering: In the realm of protein engineering, researchers leverage Fmoc-Val-Ala-OH to introduce specific amino acid sequences into target proteins. By incorporating this dipeptide, scientists can manipulate the structure and functionality of proteins, facilitating the study of their properties or the design of novel proteins with unique characteristics.
Biophysical Studies: Delving into biophysical studies, Fmoc-Val-Ala-OH serves as a tool for investigating peptide folding, stability, and interactions. By synthesizing peptides containing this dipeptide, researchers can explore their conformational dynamics under diverse conditions. This in-depth understanding is crucial for unravelling the complexities of protein folding disorders and formulating effective therapeutic strategies.
Drug Discovery: Through the creation of peptide libraries using combinatorial chemistry, researchers can screen for peptides exhibiting high affinity and specificity towards target molecules. These peptide drugs hold the potential to function as inhibitors, activators, or signaling molecules in therapeutic contexts, offering promising avenues for innovative drug interventions.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
