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Fmoc-Val-Ala-Gly-OH

  CAS No.: 2377585-15-2   Cat No.: BADC-01484 4.5  

Fmoc-Val-Ala-Gly-OH is a noteworthy peptide in the realm of biomedicine and stands out as a pivotal player in combating a myriad of ailments. Its distinctive amalgamation of amino acids not only showcases formidable potential in intricately honing drug delivery mechanisms but also towards the noble pursuit of alleviating cancerous maladies and grappling with autoimmune disorders.

Fmoc-Val-Ala-Gly-OH

Structure of 2377585-15-2

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ADC Linker
Molecular Formula
C25H29N3O6
Molecular Weight
467.51

* For research and manufacturing use only. We do not sell to patients.

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Synonyms
N-(fluorenylmethoxycarbonyl)-L-valyl-L-alanyl-glycine
IUPAC Name
2-[[(2S)-2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]propanoyl]amino]acetic acid
Canonical SMILES
CC(C)C(C(=O)NC(C)C(=O)NCC(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
InChI
InChI=1S/C25H29N3O6/c1-14(2)22(24(32)27-15(3)23(31)26-12-21(29)30)28-25(33)34-13-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,14-15,20,22H,12-13H2,1-3H3,(H,26,31)(H,27,32)(H,28,33)(H,29,30)/t15-,22-/m0/s1
InChIKey
WWKPUJPFRDGCJU-NYHFZMIOSA-N
Appearance
White Solid

Fmoc-Val-Ala-Gly-OH, a versatile peptide with wide-ranging scientific and industrial uses, plays a crucial role in numerous innovative applications. Here are four key applications of Fmoc-Val-Ala-Gly-OH:

Peptide Synthesis: Serving as a fundamental component in solid-phase peptide synthesis (SPPS), Fmoc-Val-Ala-Gly-OH enables researchers to construct tailored peptides for experimental investigations. By integrating this tripeptide into elongated peptide sequences, scientists can explore protein interactions, enzyme substrates, and receptor binding.

Drug Delivery Research: In the realm of drug delivery, Fmoc-Val-Ala-Gly-OH becomes a valuable tool for designing peptide-based carriers for targeted drug transport systems. These peptide conveyors enhance the solubility, stability, and bioavailability of therapeutic substances, especially for directing drugs to specific tissues or cells.

Biomaterials Development: Fmoc-Val-Ala-Gly-OH finds utility in the fabrication of biomaterials crucial for tissue engineering and regenerative medicine. When incorporated into hydrogels or scaffolds, this peptide fosters cell adhesion, proliferation, and differentiation, fundamental for crafting synthetic tissues and organs vital for transplantation and disease replication.

Bioconjugation: In bioconjugation endeavors, Fmoc-Val-Ala-Gly-OH is amenable to functionalization for linking diverse molecules like fluorescent dyes, drugs, or affinity tags to larger biomolecular structures. This process facilitates the monitoring, imaging, and targeted delivery of these conjugates within biological systems. Leveraging this tripeptide scaffold, researchers can synthesize multifunctional molecules tailored for diagnostic and therapeutic advances.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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