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H-GGFG-Glycolic acid

  CAS No.: 1599440-20-6   Cat No.: BADC-01481 4.5  

H-GGFG-glycolic acid is an outstanding biomedical chemical that has shown efficacy in drug development for a variety of skin diseases. This particular compound has unique exfoliating properties, making it very effective at fighting acne, reducing wrinkles, and lightening pigmentation. In addition, H-GGFG-glycolic acid is a widely used cleavable ADC linker.

H-GGFG-Glycolic acid

Structure of 1599440-20-6

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ADC Linker
Molecular Formula
C18H25N5O7
Molecular Weight
423.42

* For research and manufacturing use only. We do not sell to patients.

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Popular Publications Citing BOC Sciences Products
Synonyms
Gly-Gly-L-Phe-N-[(carboxymethoxy)methyl]Glycinamide; (S)-16-Amino-10-benzyl-6,9,12,15-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-1-oic acid
IUPAC Name
2-[[[2-[[(2S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]methoxy]acetic acid
Canonical SMILES
C1=CC=C(C=C1)CC(C(=O)NCC(=O)NCOCC(=O)O)NC(=O)CNC(=O)CN
InChI
InChI=1S/C18H25N5O7/c19-7-14(24)20-9-16(26)23-13(6-12-4-2-1-3-5-12)18(29)21-8-15(25)22-11-30-10-17(27)28/h1-5,13H,6-11,19H2,(H,20,24)(H,21,29)(H,22,25)(H,23,26)(H,27,28)/t13-/m0/s1
InChIKey
JKVPATHZQGMASP-ZDUSSCGKSA-N
Appearance
White Solid
Boiling Point
971.9±65.0 °C at 760 mmHg

H-GGFG-Glycolic acid, a compound merging a peptide sequence with glycolic acid, finds wide-ranging applications in diverse scientific and industrial realms. Here are four key applications of H-GGFG-Glycolic acid:

Skin Care and Cosmetics: A standout ingredient in skincare formulations, H-GGFG-Glycolic acid boasts exfoliating and anti-aging virtues. Its prowess lies in sloughing off dead skin cells, fostering skin rejuvenation, and enhancing skin texture and tone. This compound finds its way into wound healing balms and anti-aging creams, aiding in the restoration of skin vitality and radiance.

Drug Delivery Systems: In the domain of pharmaceutical research, H-GGFG-Glycolic acid emerges as a pivotal component of drug delivery systems, elevating the stability and efficacy of therapeutic agents. The peptide sequence lends itself to targeted drug delivery and controlled release mechanisms, thereby augmenting medication bioavailability and curtailing systemic side effects.

Biomedical Research: A staple in biomedical investigations, H-GGFG-Glycolic acid plays a crucial role in exploring the intricate ballet of peptide-cell interactions. As a model compound, it sheds light on peptide transport dynamics across cellular barriers and illuminates their potential as therapeutic modalities. Researchers harness this compound to unravel the mysteries of cellular uptake routes and peptide durability.

Tissue Engineering: Within the realm of tissue engineering, H-GGFG-Glycolic acid becomes a linchpin in scaffold materials, fostering cell adhesion and proliferation. The glycolic acid segment furnishes a biodegradable scaffold while the peptide sequence nurtures cellular interplay. This synergy propels the development of biomaterials for regenerative medicine applications.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Amino-PEG4-acetic acid | [2-(Fmoc-amino)acetamido]methyl Acetate | H-GGFG-Glycolic acid
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