Name: m-PEG7-Ms
Brand: BOC Sciences
Rating: 5 (1 reviews)

Synonyms

2,5,8,11,14,17,20-heptaoxadocosan-22-yl methanesulfonate; 2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl methanesulfonate

IUPAC Name

2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl methanesulfonate

Canonical SMILES

COCCOCCOCCOCCOCCOCCOCCOS(=O)(=O)C

InChI

InChI=1S/C16H34O10S/c1-19-3-4-20-5-6-21-7-8-22-9-10-23-11-12-24-13-14-25-15-16-26-27(2,17)18/h3-16H2,1-2H3

InChIKey

ABSVPRBGVPHWDJ-UHFFFAOYSA-N

Solubility

10 mm in DMSO

PSA

116.36000

Appearance

Solid

Shelf Life

0-4°C for short term (days to weeks), or -20°C for long term (months).

Shipping

Room temperature, or blue ice upon request.

Storage

Store at -20 °C, keep in dry and avoid sunlight.

Form

Solid

m-PEG7-Ms, also known as methoxy-polyethylene glycol methylsulfonate, is a versatile compound widely embraced in the biosciences for its remarkable capabilities in modifying and enhancing biological molecules. Here are four key applications of m-PEG7-Ms:

Protein PEGylation: Embracing m-PEG7-Ms in the realm of protein PEGylation, scientists engage in a meticulous process of affixing polyethylene glycol chains to protein molecules. This transformative modification elevates the stability and solubility of proteins, diminishing their immunogenicity while elongating their half-life in the bloodstream. Consequently, PEGylated proteins emerge as favorable candidates in therapeutic realms, especially within drug delivery systems, offering enhanced treatment options.

Drug Delivery Systems: Within the intricate domain of drug delivery, m-PEG7-Ms serves as a pivotal linker, bridging drugs with polymers to amplify their therapeutic potency and bioavailability. By enveloping the drug with a protective hydrophilic shield, m-PEG7-Ms minimizes degradation and swift clearance rates, paving the path for controlled drug release and precise targeted delivery.

Nanoparticle Functionalization: Delving into the domain of nanoparticle functionalization, m-PEG7-Ms emerges as a game-changer, enhancing biocompatibility and stability. Through the strategic modification of nanoparticle surfaces with PEG chains, these particles attain a stealth-like characteristic, evading immune system recognition and clearance.

Surface Coating in Biosensors: In the realm of biosensors, m-PEG7-Ms takes center stage, offering a shield against non-specific binding and fouling that could compromise sensor performance. The inherent hydrophilic nature of PEG preserves the bioactivity of sensors while extending their functional lifespan. This critical application plays a pivotal role in elevating the sensitivity and accuracy of biosensors utilized in crucial domains such as clinical diagnostics and environmental monitoring.