2,5-Dioxopyrrolidin-1-yl 3-(4-Methoxyphenoxy)propanoate is an NHS ester ADC linker enabling stable conjugation through phenolic groups, enhancing antibody-drug conjugate payload attachment and targeted therapeutic efficacy.
Structure of 1199815-10-5
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Capabilities & Facilities
2,5-Dioxopyrrolidin-1-yl 3-(4-Methoxyphenoxy)propanoate is a versatile chemical compound with diverse applications across scientific domains. Here are four key applications presented with high perplexity and burstiness:
Organic Synthesis: Serving as a pivotal reagent in organic synthesis, this compound plays a crucial role in incorporating 3-(4-Methoxyphenoxy)propanoic acid residues into complex molecules. Its function as an activated ester facilitates the synthesis of amide bonds, particularly valuable in crafting intricate organic structures ranging from pharmaceuticals to natural products.
Pharmaceutical Development: Within the pharmaceutical realm, 2,5-Dioxopyrrolidin-1-yl 3-(4-Methoxyphenoxy)propanoate emerges as a key player in the synthesis of novel drug candidates. It acts as an intermediary in producing bioactive compounds, enhancing their pharmacological efficacy. This compound enables the tailored generation of therapeutic agents with improved potency and specificity.
Bioconjugation: In the realm of bioconjugation methodologies, this compound finds utility in linking biomolecules, like peptides, proteins, or antibodies, to diverse substrates. The reactive ester group present in the compound facilitates the conjugation of targeting molecules to carriers, probes, or coatings. This process is instrumental in developing precision-targeted drug delivery systems and diagnostic platforms.
Polymer Chemistry: Beyond pharmaceutical applications, 2,5-Dioxopyrrolidin-1-yl 3-(4-Methoxyphenoxy)propanoate also plays a vital role in polymer chemistry. It serves as a versatile component in generating functionalized polymers, acting either as a crosslinker or monomer. These tailored polymers exhibit specific properties, ideal for applications in biomedical devices, drug delivery systems, and advanced materials engineering.
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