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NHS-SS-Ph

  CAS No.: 2750799-12-1   Cat No.: BADC-01630 4.5  

NHS-SS-Ph is a cleavable ADC linker featuring a disulfide bond and NHS ester for stable antibody conjugation and controlled intracellular drug release in targeted cancer therapies.

NHS-SS-Ph

Structure of 2750799-12-1

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Category
ADC Linker
Molecular Formula
C16H17NO7S2
Molecular Weight
399.44

* For research and manufacturing use only. We do not sell to patients.

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Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
IUPAC Name
2-[2-(2,5-dioxopyrrolidin-1-yl)oxycarbonyloxyethyldisulfanyl]ethyl benzoate
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)OCCSSCCOC(=O)C2=CC=CC=C2
InChI
InChI=1S/C16H17NO7S2/c18-13-6-7-14(19)17(13)24-16(21)23-9-11-26-25-10-8-22-15(20)12-4-2-1-3-5-12/h1-5H,6-11H2
InChIKey
VCMZIGLIZQEWHS-UHFFFAOYSA-N
Appearance
Colorless to light yellow Oil

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Acid-PEG2-SS-PEG2-acid | Azidoethyl-SS-propionic acid | Azido-C2-SS-PEG2-C2-acid | Propargyl-PEG1-SS-PEG1-PFP ester | Propargyl-PEG1-SS-PEG1-propargyl | Hydroxy-PEG3-SS-PEG3-alcohol | Propargyl-PEG1-SS-PEG1-acid | Acid-PEG3-SS-PEG3-acid | Propargyl-PEG1-SS-alcohol | Alkyne-SS-COOH | NHS-SS-Ph
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