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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

  CAS No.: 1599440-25-1   Cat No.: BADC-00971   Purity: >98.0% 4.5  

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a peptide-based cleavable linker designed for cathepsin-sensitive drug release in antibody-drug conjugates. Suitable for tumor-selective delivery.

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

Structure of 1599440-25-1

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Category
ADC Linker
Molecular Formula
C28H36N6O10
Molecular Weight
616.62
Shipping
Room temperature
Shipping
Store at -20 °C, keep in dry and avoid sunlight.

* For research and manufacturing use only. We do not sell to patients.

Size Price Stock Quantity
10 mg $939 In stock

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Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
Synonyms
Glycinamide,N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy) methyl]-
IUPAC Name
2-[[(2-amino-2-oxoethyl)-[(2S)-2-[[2-[[2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]methoxy]acetic acid
Canonical SMILES
C1=CC=C(C=C1)CC(C(=O)N(CC(=O)N)COCC(=O)O)NC(=O)CNC(=O)CNC(=O)CCCCCN2C(=O)C=CC2=O
InChI
InChI=1S/C28H36N6O10/c29-21(35)16-33(18-44-17-27(41)42)28(43)20(13-19-7-3-1-4-8-19)32-24(38)15-31-23(37)14-30-22(36)9-5-2-6-12-34-25(39)10-11-26(34)40/h1,3-4,7-8,10-11,20H,2,5-6,9,12-18H2,(H2,29,35)(H,30,36)(H,31,37)(H,32,38)(H,41,42)/t20-/m0/s1
InChIKey
KESCPWCFEIIACU-FQEVSTJZSA-N
Density
1.341±0.06 g/cm3(Predicted)
Solubility
10 mm in DMSO
Appearance
Solid
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
Room temperature
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Boiling Point
1137.9±65.0°C(Predicted)
Form
Solid

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH, a peptide-based compound, with diverse applications in scientific and medical fields.

Protein Structure Analysis: With intricate precision, MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH acts as a model compound, shedding light on the complexities of protein folding and stability. By deeply examining its structure and interactions, researchers unveil profound insights into peptide behavior and the core tenets of protein architecture.

Drug Delivery Systems: Venturing into the realm of drug delivery, MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH emerges as a versatile tool for designing sophisticated drug delivery systems. Leveraging its peptide backbone as a biodegradable and biocompatible conduit for pharmaceutical transport, this compound enables the development of targeted and controlled release mechanisms.

Bioconjugation Studies: With its unique structural composition, this peptide stands as a catalyst for bioconjugation explorations, where it can be intricately linked to various biomolecules like antibodies or enzymes for diverse diagnostic and therapeutic applications. The revelations stemming from its interactions with other biomolecules hold the promise of spearheading innovative biomedical tools and interventions.

Biomaterial Engineering: Positioned at the forefront of biomaterial engineering, MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH emerges as a transformative force in crafting novel materials for medical implants and tissue scaffolding. Its adaptable peptide structure welcomes modifications that enhance mechanical properties and biological compatibility, ushering in groundbreaking developments in regenerative medicine and cutting-edge biomedical devices. This compound propels the field of medical engineering forward with unparalleled ingenuity and precision.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: 1-BOC-Azetidine-3-carboxylic acid methyl ester | Mc-Gly-Gly-Phe-Gly-PAB-OH TFA | H-L-Lys(N3-Gly)-OH hydrochloride | trans-Cyclooctene-PEG(3)-maleimide | H-L-Lys(4-N3-Z)-OH HCl | MC-Gly-Gly-D-Phe | Boc-L-Tyr(PEG(3)-N3)-OH | Mc-Gly-Gly-Phe-Gly-PAB-OH | Poc-Cystamine | Boc-Val-Ala-PAB | MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
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