MC-Gly-Gly-Phe - CAS 1599440-15-9
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MC-Gly-Gly-Phe - CAS 1599440-15-9 Catalog number: BADC-00970

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MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).

Category
ADCs Linker
Product Name
MC-Gly-Gly-Phe
CAS
1599440-15-9
Catalog Number
BADC-00970
Molecular Formula
C23H28N4O7
Molecular Weight
472.49
Purity
>96.0%

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Description
MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).
Synonyms
(2S)-2-[[2-[[2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]acetyl]amino]acetyl]amino]-3-phenylpropanoic acid
IUPAC Name
(2S)-2-[[2-[[2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]acetyl]amino]acetyl]amino]-3-phenylpropanoic acid
Canonical SMILES
C1=CC=C(C=C1)CC(C(=O)O)NC(=O)CNC(=O)CNC(=O)CCCCCN2C(=O)C=CC2=O
InChI
InChI=1S/C23H28N4O7/c28-18(9-5-2-6-12-27-21(31)10-11-22(27)32)24-14-19(29)25-15-20(30)26-17(23(33)34)13-16-7-3-1-4-8-16/h1,3-4,7-8,10-11,17H,2,5-6,9,12-15H2,(H,24,28)(H,25,29)(H,26,30)(H,33,34)/t17-/m0/s1
InChIKey
NFVPAFLSJIPUCL-KRWDZBQOSA-N
Solubility
DMSO: 50 mg/ml (10582 mm, need ultrasonic)
Appearance
Solid
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
Room temperature, or blue ice upon request.
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Form
Solid
Biological Activity
MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Calculate
The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Calculate

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Historical Records: MC-Alkyl-Hydrazine Modified MMAF | (2S,3R)-H-Abu(3-N3)-OH (hydrochloride) | MC-Gly-Gly-Phe
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