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N-(2-(2,3-Dimethylphenoxy)ethyl)-4-Formylbenzamide

  CAS No.: 1226305-75-4   Cat No.: BADC-00559 4.5  

N-(2-(2,3-Dimethylphenoxy)ethyl)-4-Formylbenzamide is an aldehyde-functional ADC linker supporting selective conjugation and improved stability, boosting antibody-drug conjugate specificity and cytotoxic payload delivery.

N-(2-(2,3-Dimethylphenoxy)ethyl)-4-Formylbenzamide

Structure of 1226305-75-4

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ADC Linker
Molecular Formula
C18H19NO3
Molecular Weight
297.35
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Room temperature, or blue ice upon request.

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IUPAC Name
N-[2-(2,3-dimethylphenoxy)ethyl]-4-formylbenzamide
Canonical SMILES
CC1=C(C(=CC=C1)OCCNC(=O)C2=CC=C(C=C2)C=O)C
InChI
InChI=1S/C18H19NO3/c1-13-4-3-5-17(14(13)2)22-11-10-19-18(21)16-8-6-15(12-20)7-9-16/h3-9,12H,10-11H2,1-2H3,(H,19,21)
InChIKey
WRRRKXDPJGOKGD-UHFFFAOYSA-N
Shipping
Room temperature, or blue ice upon request.

Pharmaceutical Applications: N-(2-(2,3-Dimethylphenoxy)ethyl)-4-Formylbenzamide has significant potential in the pharmaceutical industry due to its bioactive structure. The combination of a formylbenzamide group and a dimethylphenoxyethyl moiety provides the compound with the ability to interact with various biological targets. It has been explored for its anti-inflammatory and antioxidant properties, making it a potential candidate for treating inflammatory diseases, such as arthritis or other chronic inflammatory conditions. Additionally, its structural similarity to other bioactive molecules suggests it could have anticancer activity, with studies indicating that it may influence cell signaling pathways involved in apoptosis and tumor progression. This makes it a promising compound for further development as a therapeutic agent for cancer or autoimmune diseases.

Chemical Biology and Drug Discovery: In chemical biology, N-(2-(2,3-Dimethylphenoxy)ethyl)-4-Formylbenzamide serves as a valuable tool in drug discovery and molecular probing. Its distinct chemical structure allows it to be used in high-throughput screening assays to identify novel bioactive molecules. The compound’s ability to bind to specific enzymes or receptors could help pinpoint new therapeutic targets, assisting in the development of more effective drugs. Furthermore, its bioactive potential makes it a useful lead compound in designing drugs that target specific diseases at the molecular level, particularly in the context of precision medicine. Researchers are exploring its role in modulating key biochemical pathways, making it an exciting candidate for future drug discovery programs.

Material Science and Synthesis: N-(2-(2,3-Dimethylphenoxy)ethyl)-4-Formylbenzamide also finds applications in materials science, particularly in the synthesis of functionalized materials. Its aromatic formyl group and phenoxyethyl chain enable it to be used as a building block for the development of advanced polymers and composites with tailored properties. The compound’s ability to form stable bonds with other molecules can be leveraged in creating self-assembled materials, coatings, or sensor platforms. Such materials can have applications in a wide range of industries, including electronics, catalysis, and nanotechnology, where functionalized surfaces are required for enhanced performance. This versatile compound is therefore valuable not only in pharmaceuticals but also in material design and innovation.

Cosmetic and Dermatological Uses: N-(2-(2,3-Dimethylphenoxy)ethyl)-4-Formylbenzamide’s ability to influence cellular behavior also opens up potential applications in the cosmetic and dermatological industries. Its anti-inflammatory and antioxidant properties suggest it could be an effective ingredient in skincare products, particularly for reducing signs of aging or treating skin conditions like acne or eczema. By modulating oxidative stress and promoting cellular regeneration, it may help improve skin health, elasticity, and appearance. Its gentle nature could also make it suitable for sensitive skin formulations, offering a dual function of both therapeutic and cosmetic benefits. The compound’s incorporation into cosmetic products could thus address both aesthetic and medical concerns in skincare.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: (2S)-p-SCN-Bn-NOTA | [(2-methylpropan-2-yl)oxycarbonylamino] 4-methylbenzenesulfonate | Fmoc-L-Lys(4-N3-Z)-OH | p-SCN-Bn-DOTA | DM1-SMCC | DM1-SPP | (2-pyridyldithio)-PEG1-hydrazine | (R)-8-Azido-2-(Fmoc-amino)octanoic acid | N-(2-((2,3-Dihydro-1H-Inden-5-yl)oxy)ethyl)-4-Formylbenzamide | 2,5-dioxopyrrolidin-1-yl 3-(4-hydroxyphenoxy)propanoate | N-(2-(2,3-Dimethylphenoxy)ethyl)-4-Formylbenzamide
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