N-(2-(2-Chloroethoxy)ethyl)-4-formylbenzamide is a linker for antibody-drug-conjugation (ADC).
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BADC-00523 | -- | $-- | Inquiry |
Key Applications in Medicinal Chemistry: N-(2-(2-Chloroethoxy)ethyl)-4-Formylbenzamide is primarily recognized for its potential in medicinal chemistry, particularly in the design of novel drug candidates. The compound’s structure allows it to interact with biological molecules through its chloroethoxy and formylbenzamide groups, making it a versatile scaffold for synthesizing bioactive molecules. Researchers are exploring its use in the development of selective inhibitors for various enzymes, including those involved in cancer cell proliferation and inflammation. Its ability to modify cellular processes through receptor binding and enzyme inhibition is key to its therapeutic potential.
Role in Drug Delivery Systems: Another significant application of N-(2-(2-Chloroethoxy)ethyl)-4-Formylbenzamide lies in drug delivery systems. The presence of the chloroethoxy group enhances its solubility and stability in aqueous environments, making it suitable for incorporation into formulations such as liposomes or nanoparticles. This structural feature allows for controlled release and targeted drug delivery, particularly in the treatment of diseases such as cancer or neurodegenerative disorders. By improving the pharmacokinetics and bioavailability of therapeutic agents, this compound could contribute to the development of more effective treatments with reduced side effects.
Applications in Molecular Probes: In addition to its role in drug development, N-(2-(2-Chloroethoxy)ethyl)-4-Formylbenzamide is being studied as a molecular probe for detecting and analyzing specific biomolecules. The formylbenzamide group provides a reactive site that can form covalent bonds with target proteins, offering a unique method for studying protein interactions and cellular pathways. This feature is particularly valuable in proteomics and drug screening assays, where understanding the binding affinity and specificity of potential drug candidates is critical. Its potential use as a probe in various biochemical assays demonstrates its versatility in the research field.
Contribution to Anti-cancer Research: The compound's structural elements suggest it may play a role in the inhibition of key signaling pathways involved in cancer cell growth. Studies have shown that formylbenzamide derivatives exhibit activity against certain types of cancer cells, with the chloroethoxy group potentially influencing the compound's ability to cross cellular membranes and interact with intracellular targets. This opens up possibilities for N-(2-(2-Chloroethoxy)ethyl)-4-Formylbenzamide to be explored as part of next-generation cancer therapeutics. Its selective activity could help in developing treatments that minimize damage to healthy tissues while targeting cancerous cells.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.