DBM(C6)-VC-PAB-MMAE - CAS 1644228-55-6
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DBM(C6)-VC-PAB-MMAE - CAS 1644228-55-6 Catalog number: BADC-01408

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DBM(C6)-VC-PAB-MMAE is a thiol-reactive drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Cytotoxin with Linkers
Product Name
DBM(C6)-VC-PAB-MMAE
CAS
1644228-55-6
Catalog Number
BADC-01408
Molecular Formula
C68H103Br2N11O15
Molecular Weight
1474.44
DBM(C6)-VC-PAB-MMAE

Ordering Information

Catalog Number Size Price Quantity
BADC-01408 -- $--
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Description
DBM(C6)-VC-PAB-MMAE is a thiol-reactive drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
L-Valine, N-[[[4-[[N-[6-(3,4-dibromo-2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; N-[[[4-[[N-[6-(3,4-Dibromo-2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valine
IUPAC Name
4-((S)-2-((S)-2-(6-(3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl ((S)-1-(((S)-1-(((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)(methyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)(methyl)carbamate
Canonical SMILES
O=C(N)NCCCC(NC(=O)C(NC(=O)CCCCCN1C(=O)C(Br)=C(Br)C1=O)C(C)C)C(=O)NC2=CC=C(C=C2)COC(=O)N(C)C(C(=O)NC(C(=O)N(C)C(C(OC)CC(=O)N3CCCC3C(OC)C(C(=O)NC(C)C(O)C=4C=CC=CC4)C)C(C)CC)C(C)C)C(C)C
InChI
InChI=1S/C68H103Br2N11O15/c1-15-41(8)57(49(94-13)36-51(83)80-35-23-27-48(80)59(95-14)42(9)60(85)73-43(10)58(84)45-24-18-16-19-25-45)78(11)66(91)55(39(4)5)77-63(88)56(40(6)7)79(12)68(93)96-37-44-29-31-46(32-30-44)74-61(86)47(26-22-33-72-67(71)92)75-62(87)54(38(2)3)76-50(82)28-20-17-21-34-81-64(89)52(69)53(70)65(81)90/h16,18-19,24-25,29-32,38-43,47-49,54-59,84H,15,17,20-23,26-28,33-37H2,1-14H3,(H,73,85)(H,74,86)(H,75,87)(H,76,82)(H,77,88)(H3,71,72,92)/t41-,42+,43+,47-,48-,49+,54-,55-,56-,57-,58+,59+/m0/s1
InChIKey
HUVBFPTZLBVBAA-KKUITVJMSA-N
Density
1.310±0.06 g/cm3
Boiling Point
1375.2±65.0°C at 760 mmHg
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Calculate
The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Calculate

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