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MC-Ala-Ala-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01703 | -- | $-- | Inquiry |
MC-Ala-Ala-PAB, a versatile peptide-based compound, holds great promise in scientific research and potential therapeutics.
Drug Delivery Systems: Incorporating MC-Ala-Ala-PAB into drug delivery systems revolutionizes the targeted release of therapeutic agents. Serving as a peptide linker or protective group, it orchestrates controlled drug delivery at specific sites, diminishing side effects and amplifying efficacy. This technology, especially crucial in cancer treatments, ensures precise drug deployment, safeguarding healthy tissues from detrimental repercussions.
Protease Activity Assays: Serving as a substrate for protease enzymes, MC-Ala-Ala-PAB emerges as a pivotal asset in enzymatic activity assays. Researchers leverage this compound to gauge the activity of distinct proteases through cleavage monitoring, measurable via spectroscopic techniques. This application plays a pivotal role in screening protease inhibitors, vital for advancements in pharmaceutical interventions against conditions such as hypertension and viral infections.
Bioconjugation Techniques: Harnessing MC-Ala-Ala-PAB in bioconjugation methodologies enables the attachment of diverse molecules like proteins or fluorophores to peptides or other biomolecules. Its unique structure facilitates the creation of enduring conjugates, allowing precise labeling or modification of molecules for imaging or therapeutic pursuits. These techniques propel research in diagnostics and personalized medicine to new frontiers.
Anticancer Research: In the realm of oncology, MC-Ala-Ala-PAB is the subject of intense scrutiny for its potential in formulating novel anticancer agents. Its role as a prodrug component renders it ideal for crafting molecules that activate exclusively within the tumor microenvironment, minimizing systemic toxicity.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
