MC-VC-PAB-NH2 is a maleimide-activated cleavable ADC linker with Val-Cit dipeptide and PAB spacer, featuring terminal amine for efficient antibody conjugation and selective drug release.
Structure of 1616727-20-8
* For research and manufacturing use only. We do not sell to patients.
Size | Price | Stock | Quantity |
---|---|---|---|
-- | $-- | In stock |
Looking for different specifications? Click to request a custom quote!
Capabilities & Facilities
MC-VC-PAB-NH2, a chemical linker utilized in drug design, plays a pivotal role in the development of antibody-drug conjugates (ADCs).
Antibody-Drug Conjugates (ADCs) Development: MC-VC-PAB-NH2 serves as the crucial bridge linking cytotoxic drugs to antibodies, enabling targeted delivery to cancer cells while sparing healthy tissues. By facilitating precise drug targeting, this linker enhances the therapeutic index and reduces side effects significantly. Its stability and cleavage properties ensure drug release upon internalization by target cells, thereby amplifying the efficacy of cancer treatments.
Bioconjugation Studies: In the realm of bioconjugation techniques, MC-VC-PAB-NH2 plays a pivotal role in exploring protein interactions and modifications. By enabling the attachment of diverse biomolecules to proteins of interest, scientists can delve deep into protein function and structure. The utilization of linkers like MC-VC-PAB-NH2 is indispensable for biosensor and diagnostic tool development, opening new avenues in bioanalytical research.
Pharmaceutical Research: At the forefront of pharmaceutical innovation, MC-VC-PAB-NH2 is a cornerstone in the development of novel therapeutic agents. Researchers leverage its unique properties to study its behavior and interactions within biological systems, optimizing drug delivery systems. This ensures that payloads reach their designated targets with minimal degradation, propelling the evolution of next-generation therapeutics and advancing the frontiers of pharmaceutical science.
Customized Drug Delivery: MC-VC-PAB-NH2 plays a pivotal role in tailoring drug delivery platforms for specific medical conditions, offering a personalized approach to treatment. By allowing precise control over drug release and targeting, it facilitates the creation of therapies customized to individual patient needs.
Catalog | Product Name | CAS | Inquiry |
---|---|---|---|
BADC-01417 | MC-VC-PAB-DMEA-PNU159682 | 1178887-17-6 | |
BADC-01845 | MC-VC-PAB-NH2 TFA | 1616727-21-9 | |
BADC-01535 | MC-VC-PAB-Tubulysin M | 1639939-56-2 | |
BADC-00854 | Mc-VC-PAB-SN38 | 1801838-28-7 | |
BADC-01283 | MC-VC-PAB-Azide | ||
BADC-00733 | MC-vc-PAB-C6-a-amanitin | ||
BADC-00734 | MC-vc-PAB-DMEA-(PEG2)-duocarmycin SA | ||
BADC-00736 | MC-va-PAB-MMAD | ||
BADC-00739 | MC-vc-PAB-MMAD | ||
BADC-00740 | MC-vc-PAB-Auristatin 0101 |
Contact our experts today for pricing and comprehensive details on our ADC offerings.
From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.
Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.
Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.