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Fmoc-N-amido-PEG4-propionic acid

  CAS No.: 557756-85-1   Cat No.: BADC-01135   Purity: ≥95% 4.5  

Fmoc-N-amido-PEG4-propionic acid is a bifunctional PEG linker for ADC construction, offering improved aqueous solubility and flexible conjugation strategies in targeted drug delivery.

Fmoc-N-amido-PEG4-propionic acid

Structure of 557756-85-1

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Category
ADC Linker
Molecular Formula
C26H33NO8
Molecular Weight
487.54
Shipping
Room temperature
Shipping
Store at -20°C, keep in dry and avoid sunlight

* For research and manufacturing use only. We do not sell to patients.

Size Price Stock Quantity
5 g $376 In stock

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Popular Publications Citing BOC Sciences Products
Synonyms
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid; Fmoc-N-amido-PEG4-acid; Fmoc-NH-PEG4-CH2CH2COOH; Fmoc-15-Amino-4,7,10,13-tetraoxapentadecacanoic acid; 2,7,10,13,16-Pentaoxa-4-azanonadecan-19-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-; 15-(9-Fluorenylmethyloxycarbonyl)amino-4,7,10,13-tetraoxa-pentadecanoic acid; 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester; 15-(Fmoc-amino)-4,7,10,13-tetraoxapentadecanoic Acid
IUPAC Name
3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCC(=O)O
InChI
InChI=1S/C26H33NO8/c28-25(29)9-11-31-13-15-33-17-18-34-16-14-32-12-10-27-26(30)35-19-24-22-7-3-1-5-20(22)21-6-2-4-8-23(21)24/h1-8,24H,9-19H2,(H,27,30)(H,28,29)
InChIKey
NUHRPLKTAAVHCZ-UHFFFAOYSA-N
Density
1.219 g/cm3
Solubility
Soluble in DCM, DMF, DMSO
PSA
112.55000
Appearance
Pale Yellow or Colorless Oily Matter
Quantity
Data not available, please inquire.
Shelf Life
≥ 2 years
Shipping
Room temperature
Storage
Store at -20°C, keep in dry and avoid sunlight
Boiling Point
682.1±55.0 °C at 760 mmHg
Form
Solid
Biological Activity
Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Fmoc-Ala-Ala-Asn(Trt)-OH | m-PEG8-COOH | Bis-PEG1-NHS ester | m-PEG2-NHS ester | Alkyne-PEG2-iodide | Mal-PEG4-Val-Cit-PAB-OH | Amino-PEG8-propionic acid | Azido-PEG2-PFP ester | Mal-PEG4-bis-PEG3-methyltetrazine | S-methyl DM1 | Fmoc-N-amido-PEG4-propionic acid
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