t-Boc-N-amido-PEG1-bromide - CAS 164332-88-1

t-Boc-N-amido-PEG1-bromide - CAS 164332-88-1 Catalog number: BADC-00979

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t-Boc-N-amido-PEG1-bromide is a PEG linker containing a bromide group and a Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Category
ADCs Linker
Product Name
t-Boc-N-amido-PEG1-bromide
CAS
164332-88-1
Catalog Number
BADC-00979
Molecular Formula
C9H18BrNO3
Molecular Weight
268.15
Purity
>98.0%
t-Boc-N-amido-PEG1-bromide

Ordering Information

Catalog Number Size Price Quantity
BADC-00979 -- $-- Inquiry
Description
t-Boc-N-amido-PEG1-bromide is a PEG linker containing a bromide group and a Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Synonyms
Br-PEG1-NHBoc; tert-Butyl (2-(2-bromoethoxy)ethyl)carbamate; Boc-NH-PEG1-Br; N-Boc-2-(2-bromoethoxy)ethanamine; BocNH-PEG1-CH2CH2Br; Carbamic acid, N-[2-(2-bromoethoxy)ethyl]-, 1,1-dimethylethyl ester; N-Boc-PEG1-bromide; 2-Methyl-2-propanyl [2-(2-bromoethoxy)ethyl]carbamate
IUPAC Name
tert-butyl N-[2-(2-bromoethoxy)ethyl]carbamate
Canonical SMILES
CC(C)(C)OC(=O)NCCOCCBr
InChI
InChI=1S/C9H18BrNO3/c1-9(2,3)14-8(12)11-5-7-13-6-4-10/h4-7H2,1-3H3,(H,11,12)
InChIKey
DMOPZPBTLCZSGL-UHFFFAOYSA-N
Density
1.283±0.06 g/cm3 (Predicted)
Solubility
Soluble in DCM, DMF, DMSO, Water
LogP
2.31350
PSA
47.56000
Appearance
Pale Yellow or Colorless Oily Liquid
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
Room temperature, or blue ice upon request.
Storage
Store at 2-8°C, keep in dry and avoid sunlight
Pictograms
Irritant
Signal Word
Warning
Boiling Point
336.6±0.0 °C at 760 mmHg
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: t-Boc-N-amido-PEG1-bromide
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