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MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01845 | -- | $-- | Inquiry |
MC-VC-PAB-NH2 TFA is a versatile chemical linker utilized in the intricate realm of antibody-drug conjugates (ADCs) for precision-targeted cancer therapy. Here are four key applications of MC-VC-PAB-NH2 TFA:
Antibody-Drug Conjugate Development: Serving as a pivotal cleavable linker in ADC synthesis, MC-VC-PAB-NH2 TFA facilitates the delivery of cytotoxic agents exclusively to malignant cells. This strategic linker ensures the inertness of the drug until it reaches its intended destination, effectively minimizing systemic toxicity. Such targeted drug release not only amplifies the efficacy of cancer treatments but also permits the administration of higher dosages with enhanced safety margins.
Cancer Research: Delving into the intricacies of pharmacokinetics and pharmacodynamics, researchers harness MC-VC-PAB-NH2 TFA to dissect the behavior of ADCs. By scrutinizing the impact of the linker on drug kinetics and stability, scientists glean valuable insights for optimizing ADC structure and functionality. These meticulous investigations contribute to the refinement of cancer therapies, paving the way for more potent treatments with attenuated adverse effects.
Bioconjugation Techniques: At the forefront of bioconjugation methodologies, MC-VC-PAB-NH2 TFA assumes a crucial role in tethering biologically active substances to carrier systems. This capability is particularly invaluable in crafting compounds for diagnostic and imaging applications, enabling precise delivery of probes and contrast agents. The seamless bioconjugation not only heightens the specificity and sensitivity of diagnostic assays but also propels advancements in targeted therapeutic interventions.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
