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Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01174 | -- | $-- | Inquiry |
Amino-PEG4-alcohol is a versatile compound employed in various biotechnological, pharmaceutical, and material science applications. Here are some key applications of Amino-PEG4-alcohol:
Protein PEGylation: Amino-PEG4-alcohol is used for the PEGylation of therapeutic proteins, which involves attaching polyethylene glycol (PEG) chains to proteins to enhance their stability and solubility. This process helps reduce immunogenicity and prolongs the half-life of therapeutic proteins in the bloodstream. Ultimately, this leads to improved efficacy and reduced dosing frequency for protein-based therapies.
Drug Delivery Systems: Amino-PEG4-alcohol serves as a linker or spacer in the design of drug delivery systems, including nanoparticles and liposomes. Its hydrophilic nature allows for better dispersion and stability of drug carriers in aqueous environments. These systems can be engineered to achieve targeted and controlled release of drugs, enhancing therapeutic outcomes.
Bioconjugation: In bioconjugation techniques, Amino-PEG4-alcohol is often used to link biomolecules, such as antibodies, enzymes, or nucleic acids, to various surfaces or other molecules. This facilitates the creation of advanced diagnostic tools, biosensors, and bio-functional materials. The flexibility and biocompatibility of the PEG chain improve the performance and stability of the conjugated products.
Biomedical Research: Amino-PEG4-alcohol is employed in the synthesis of various biomaterials used in tissue engineering and regenerative medicine. It helps in modifying the surface properties of biomaterials to promote cell attachment, proliferation, and differentiation. This enhances the development of scaffolds and matrices that can support tissue regeneration and repair.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
