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APN-PEG36-tetrazine is a cleavable 36 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01871 | -- | $-- | Inquiry |
APN-PEG36-tetrazine, a versatile bioconjugation reagent with wide-ranging applications in science and medicine. Here are four key applications presented with high perplexity and burstiness:
Bioorthogonal Chemistry: Leveraging the unique properties of APN-PEG36-tetrazine, researchers engage in bioorthogonal chemical reactions that enable precise and efficient conjugation within biological systems, all while preserving native biochemical processes. This capability empowers the selective labeling of biomolecules within live cells and organisms with unparalleled specificity. In the realm of imaging studies and dynamic biological process tracking, this reagent plays a pivotal role.
Targeted Drug Delivery: At the forefront of precision medicine, APN-PEG36-tetrazine plays a pivotal role in targeted drug delivery by facilitating the attachment of therapeutic agents to specific cellular targets via click chemistry. This novel approach enhances the accuracy of drug delivery by conjugating drugs with targeting molecules like antibodies or peptides. The result is a targeted delivery system that ensures therapeutic agents reach their intended destination with minimal off-target effects, offering new possibilities for more effective and safer treatments, especially in complex diseases like cancer.
Nanoparticle Functionalization: Delving into the realm of nanotechnology, APN-PEG36-tetrazine serves as a key player in modifying the surface of nanoparticles, facilitating the attachment of diverse functional groups for diagnostic and therapeutic purposes. This functionalization enhances the biocompatibility, targeting precision, and stability of nanoparticles within biological environments. The resultant functionalized nanoparticles find applications in drug delivery, imaging, and biosensing, heralding a new era in nanomedicine with enhanced capabilities for personalized healthcare.
Protein and Peptide Labeling: Driving advancements in proteomics and biochemistry, APN-PEG36-tetrazine finds its niche in the precise labeling of proteins and peptides, enabling detailed analysis of protein interactions, localization, and function. Through site-specific conjugation, this reagent aids in the creation of protein conjugates that maintain their biological activity, facilitating deep dives into protein dynamics and interactions within complex biological systems. This application is indispensable for unraveling the intricacies of cellular processes and holds immense potential for advancing our understanding of fundamental biological mechanisms.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
