webinar
Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
Read More

APN-PEG4-tetrazine

  CAS No.:   Cat No.: BADC-01219   Purity: ≥95% 4.5  

APN-PEG4-tetrazine is a bioorthogonal ADC linker featuring tetrazine and PEG spacers, enabling rapid inverse-electron-demand Diels–Alder (IEDDA) click chemistry for site-specific antibody conjugation and enhanced payload delivery.

APN-PEG4-tetrazine

Structure of

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support
Category
ADC Linker
Molecular Formula
C30H33N7O6
Molecular Weight
587.63
Shipping
Room temperature, or blue ice upon request.
Storage
Store at -20 °C, keep in dry and avoid sunlight.

* For research and manufacturing use only. We do not sell to patients.

Size Price Stock Quantity
-- $-- In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
Solubility
10 mm in DMSO
Shelf Life
-20°C 3 years powder; -80°C 2 years in solvent
Shipping
Room temperature, or blue ice upon request.
Storage
Store at -20 °C, keep in dry and avoid sunlight.

APN-PEG4-tetrazine is a versatile chemical linker used in bioconjugation and molecular imaging applications. Here are some key applications of APN-PEG4-tetrazine:

Drug Delivery Systems: APN-PEG4-tetrazine enables the precise conjugation of therapeutic agents to target molecules, improving drug delivery efficiency. By attaching drugs to specific biomolecules, this linker helps in directing the drug to the desired location within the body. This targeted delivery can enhance therapeutic efficacy and minimize off-target effects.

Bioconjugation: The use of APN-PEG4-tetrazine in bioconjugation allows for the stable linkage of proteins, peptides, or other biomolecules. This method facilitates the creation of multifunctional biomolecules for various applications. This conjugation technique is widely employed in the development of diagnostics, therapeutics, and biomaterials.

Molecular Imaging: APN-PEG4-tetrazine is utilized in molecular imaging to attach fluorescent dyes or radioactive labels to specific biomolecules. This enables researchers to visualize and track biological processes in real-time. The high specificity and stability of this linker enhance the accuracy and resolution of imaging studies.

Proteomics: In proteomic research, APN-PEG4-tetrazine aids in the study of protein interactions and functions. By conjugating probes to target proteins, scientists can investigate protein networks and their roles in cellular processes. This information is crucial for understanding disease mechanisms and identifying potential therapeutic targets.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Contact our experts today for pricing and comprehensive details on our ADC offerings.

You May Also Be Interested In

From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.

ADC Linker Development Enzyme Cleavable Linker Cathepsin B Cleavable Linker Phosphatase Cleavable Linker β-Glucuronide Linker β-Galactosidase Cleavable Linker Sulfatase Cleavable Linker Chemically Cleavable Linker Non-Cleavable Linker Services Acid Cleavable Linker

Unlock Deeper ADC Insights

Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.

Linkers - A Crucial Factor in Antibody–Drug Conjugates In-Depth Review of ADC Linkers: Types, Mechanisms, and Research Progress New Structural Insights Solve Instability Issues of Maleimide Linkers in ADCs PEG Linkers in Antibody-Drug Conjugates Peptide Linkers in Antibody-Drug Conjugates Disulfide Linkers in Antibody-Drug Conjugates Biotinylation Reagents in Antibody-Drug Conjugates Maleimide Linkers in Antibody-Drug Conjugates Current ADC Linker Chemistry SPDB Linkers in Antibody-Drug Conjugates

Explore More ADC Products

Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.

ADC Cytotoxin

Powerful Targeted Cancer Solutions

ADC  Cytotoxin with Linker

Enhanced Stability And Efficacy

ADC Linker

Precise Conjugation For Success

Antibody-Drug  Conjugates (ADCs)

Maximized Therapeutic Performance

Auristatins

Next-Level Tubulin Inhibition

Calicheamicins

High-Impact DNA Targeting

Camptothecins

Advanced Topoisomerase Inhibition

Daunorubicins / Doxorubicins

Trusted Anthracycline Payloads

Duocarmycins

Potent DNA Alkylation Agents

Maytansinoids

Superior Microtubule Disruption

Pyrrolobenzodiazepines

Ultra-Potent DNA Crosslinkers

Traditional Cytotoxic Agents

Proven Chemotherapy Solutions

Cleavable Linker

Precise Intracellular Drug Release

Non-Cleavable Linker

Exceptional Long-Term Stability

Historical Records: Amino-ethyl-SS-PEG3-NHBoc | DBCO-NHCO-PEG4-NHS ester | Fmoc-D-Dbu(N3)-OH | Fmoc-D-Trp(Boc)-OH | Fmoc-D-Lys(pentynoyl)-OH | Fmoc-EDA-N3 | Fmoc-L-Lys(4-N3-Z)-OH | Aminooxy-PEG4-alcohol | Tr-PEG8-OH | (R)-8-Azido-2-(Fmoc-amino)octanoic acid | APN-PEG4-tetrazine
Send Inquiry
Verification code
Inquiry Basket