APN-PEG4-tetrazine is a bioorthogonal ADC linker featuring tetrazine and PEG spacers, enabling rapid inverse-electron-demand Diels–Alder (IEDDA) click chemistry for site-specific antibody conjugation and enhanced payload delivery.
Structure of
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Capabilities & Facilities
APN-PEG4-tetrazine is a versatile chemical linker used in bioconjugation and molecular imaging applications. Here are some key applications of APN-PEG4-tetrazine:
Drug Delivery Systems: APN-PEG4-tetrazine enables the precise conjugation of therapeutic agents to target molecules, improving drug delivery efficiency. By attaching drugs to specific biomolecules, this linker helps in directing the drug to the desired location within the body. This targeted delivery can enhance therapeutic efficacy and minimize off-target effects.
Bioconjugation: The use of APN-PEG4-tetrazine in bioconjugation allows for the stable linkage of proteins, peptides, or other biomolecules. This method facilitates the creation of multifunctional biomolecules for various applications. This conjugation technique is widely employed in the development of diagnostics, therapeutics, and biomaterials.
Molecular Imaging: APN-PEG4-tetrazine is utilized in molecular imaging to attach fluorescent dyes or radioactive labels to specific biomolecules. This enables researchers to visualize and track biological processes in real-time. The high specificity and stability of this linker enhance the accuracy and resolution of imaging studies.
Proteomics: In proteomic research, APN-PEG4-tetrazine aids in the study of protein interactions and functions. By conjugating probes to target proteins, scientists can investigate protein networks and their roles in cellular processes. This information is crucial for understanding disease mechanisms and identifying potential therapeutic targets.
Catalog | Product Name | CAS | Inquiry |
---|---|---|---|
BADC-01216 | APN-PEG4-Amine hydrochloride | ||
BADC-01217 | APN-PEG4-BCN | ||
BADC-01218 | APN-PEG4-DBCO | ||
BADC-01871 | APN-PEG36-tetrazine |
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