Fmoc-N-amido-PEG3-propionic acid - CAS 867062-95-1
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Fmoc-N-amido-PEG3-propionic acid - CAS 867062-95-1 Catalog number: BADC-01171

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Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
Fmoc-N-amido-PEG3-propionic acid
CAS
867062-95-1
Catalog Number
BADC-01171
Molecular Formula
C24H29NO7
Molecular Weight
443.49
Purity
≥95%
Fmoc-N-amido-PEG3-propionic acid

Ordering Information

Catalog Number Size Price Quantity
BADC-01171 -- $-- Inquiry

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Description
Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid; Fmoc-N-amido-PEG3-acid; Fmoc-NH-PEG3-CH2CH2COOH; Fmoc-PEG3-propionic acid; 12-(Fmoc-amino)-4,7,10-trioxadodecanoic Acid; 5,8,11-Trioxa-2-azatetradecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester; N-Fmoc-12-amino-4,7,10-trioxadodecanoic acid; 12-[(9H-Fluorene-9-yl)methoxycarbonylamino]-4,7,10-trioxadodecanoic acid; N-Fmoc-12-amino-4,7,10-trioxadodecanoic acid
IUPAC Name
3-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCC(=O)O
InChI
InChI=1S/C24H29NO7/c26-23(27)9-11-29-13-15-31-16-14-30-12-10-25-24(28)32-17-22-20-7-3-1-5-18(20)19-6-2-4-8-21(19)22/h1-8,22H,9-17H2,(H,25,28)(H,26,27)
InChIKey
CHIDDYZONKDHLG-UHFFFAOYSA-N
Density
1.230±0.06 g/cm3 (Predicted)
Solubility
Soluble in DMSO (Sparingly), Methanol (Slightly)
Melting Point
43-46°C
Flash Point
348.0±31.5 °C
Index Of Refraction
1.562
LogP
2.66
PSA
103.32000
Vapor Pressure
0.0±2.1 mmHg at 25°C
Appearance
Pale Yellow or Colorless Oily Matter
Shipping
-20°C (International: -20°C)
Storage
Store at 2-8°C under inert atmosphere
Boiling Point
651.9±55.0 °C at 760 mmHg
Form
Solid
Biological Activity
Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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