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Val-cit-PAB-OH - CAS 159857-79-1
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Val-cit-PAB-OH - CAS 159857-79-1 Catalog number: BADC-00708

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Val-cit-PAB-OH is a protease cleavable linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
Val-cit-PAB-OH
CAS
159857-79-1
Catalog Number
BADC-00708
Molecular Formula
C18H29N5O4
Molecular Weight
379.46
Purity
95%
Val-cit-PAB-OH

Ordering Information

Catalog Number Size Price Quantity
BADC-00708 100 mg $188 Inquiry
BADC-00708 5 g $249 Inquiry

Related Molecules

Catalog Product Name CAS
BADC-01679 Mal-PEG2-Val-Cit-PABA-PNP 1345681-52-8 Inquiry
BADC-00929 Fmoc-D-Val-Cit-PAB 1350456-65-3 Inquiry
BADC-00849 Acetylene-linker-Val-Cit-PABC-MMAE 1411977-95-1 Inquiry

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Description
Val-cit-PAB-OH is a protease cleavable linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
L-valyl-N5-carbamoyl-N-[4-(hydroxymethyl)phenyl]-L-omithinamide; Val-cit-PAB; (S)-2-((S)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide
IUPAC Name
(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-(carbamoylamino)-N-[4-(hydroxymethyl)phenyl]pentanamide
Canonical SMILES
CC(C)C(C(=O)NC(CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)N
InChI
InChI=1S/C18H29N5O4/c1-11(2)15(19)17(26)23-14(4-3-9-21-18(20)27)16(25)22-13-7-5-12(10-24)6-8-13/h5-8,11,14-15,24H,3-4,9-10,19H2,1-2H3,(H,22,25)(H,23,26)(H3,20,21,27)/t14-,15-/m0/s1
InChIKey
VEGGTWZUZGZKHY-GJZGRUSLSA-N
Density
1.243±0.06 g/cm3
Solubility
Soluble to ≥ 59 mg/ml in DMSO
Melting Point
715.0±60.0 °C | Condition: Press: 760 Torr
Appearance
White to off-white solid
Quantity
Grams-Kilos
Shelf Life
2 years
Shipping
-20°C (International: -20°C)
Storage
-20°C
Pictograms
Irritant
Signal Word
Warning
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Calculate
The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: 3-Azidopropionic Acid Sulfo-NHS ester | Vat-Cit-PAB-MMAD | Auristatin F | Ald-Ph-amido-PEG2-C2-Pfp ester | 3-Azido-N-Boc-D-Alanine | PEG4-aminooxy-MMAF | perfluorophenyl 1-(1,3-dioxoisoindolin-2-yloxy)-3,6,9,12-tetraoxapentadecan-15-oate | Fmoc-GGFG-PAB-OH | Biotin-PEG3-Me-Tet | Biotin-PEG(4)-SS-Azide | Val-cit-PAB-OH
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