webinar
August 17–21, 2025, Washington, DC, USA - Visit us at Booth 2230.
Read More
Val-cit-PAB-OH - CAS 159857-79-1
  1. Home
  2. Products
  3. ADCs Linker
  4. Cleavable Linkers
  5. Val-cit-PAB-OH

Val-cit-PAB-OH - CAS 159857-79-1 Catalog number: BADC-00708

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Val-cit-PAB-OH is a protease cleavable linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
Val-cit-PAB-OH
CAS
159857-79-1
Catalog Number
BADC-00708
Molecular Formula
C18H29N5O4
Molecular Weight
379.46
Purity
95%
Val-cit-PAB-OH

Ordering Information

Catalog Number Size Price Quantity
BADC-00708 100 mg $188 Inquiry
BADC-00708 5 g $249 Inquiry

Related Molecules

Catalog Product Name CAS
BADC-01679 Mal-PEG2-Val-Cit-PABA-PNP 1345681-52-8 Inquiry
BADC-00929 Fmoc-D-Val-Cit-PAB 1350456-65-3 Inquiry
BADC-00849 Acetylene-linker-Val-Cit-PABC-MMAE 1411977-95-1 Inquiry

Featured Recommendations

Recommended Services
ADC Linkers Development Antibody Modification and Conjugation ADC Analysis and Characterization ADC Linker and Cytotoxin Conjugations ADC Payloads Development ADC Manufacture ADC Development for Targets ADC Development Platform
Other Types of Linkers
Cleavable Linkers Non-cleavable Linkers
Description
Val-cit-PAB-OH is a protease cleavable linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
L-valyl-N5-carbamoyl-N-[4-(hydroxymethyl)phenyl]-L-omithinamide; Val-cit-PAB; (S)-2-((S)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide
IUPAC Name
(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-(carbamoylamino)-N-[4-(hydroxymethyl)phenyl]pentanamide
Canonical SMILES
CC(C)C(C(=O)NC(CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)N
InChI
InChI=1S/C18H29N5O4/c1-11(2)15(19)17(26)23-14(4-3-9-21-18(20)27)16(25)22-13-7-5-12(10-24)6-8-13/h5-8,11,14-15,24H,3-4,9-10,19H2,1-2H3,(H,22,25)(H,23,26)(H3,20,21,27)/t14-,15-/m0/s1
InChIKey
VEGGTWZUZGZKHY-GJZGRUSLSA-N
Density
1.243±0.06 g/cm3
Solubility
Soluble to ≥ 59 mg/ml in DMSO
Melting Point
715.0±60.0 °C | Condition: Press: 760 Torr
Appearance
White to off-white solid
Quantity
Grams-Kilos
Shelf Life
2 years
Shipping
-20°C (International: -20°C)
Storage
-20°C
Pictograms
Irritant
Signal Word
Warning
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Calculate
The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Calculate

Related Products

Gly-Gly-Phe-OH
Gly-Gly-Phe-OH
(CAS: 6234-26-0)
Amino-PEG4-propionic acid
Amino-PEG4-propionic acid
(CAS: 663921-15-1)
t-Boc-N-amido-PEG7-alcohol
t-Boc-N-amido-PEG7-alcohol
(CAS: 1292268-13-3)
DBCO-NHS ester
DBCO-NHS ester
(CAS: 1353016-71-3)
(2S,2'S)-Bis(2,5-dioxopyrrolidin-1-Yl) 4,4'-disulfanediylbis(2-(((benzyloxy)carbonyl)amino)butanoate)
(2S,2'S)-Bis(2,5-dioxopyrrolidin-1-Yl) 4,4'-disulfanediylbis(2-(((benzyloxy)carbonyl)amino)butanoate)
(CAS: 299402-08-7)
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
(CAS: 1599440-25-1)
Historical Records: Propargyl-PEG8-amine | MA-PEG8-VA-PAB-SG3199 | Val-cit-PAB-OH
Why Choose BOC Sciences?

Customer Support

Providing excellent 24/7 customer service and support

Project Management

Offering 100% high-quality services at all stages

Quality Assurance

Ensuring the quality and reliability of products or services

Global Delivery

Ensuring timely delivery of products worldwide

Featured Services
cGMP Grade Products

BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
Site-Specific Conjugation

BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, non-natural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
Linkers for Bioconjugation

BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
ADC Targets
Questions & Comments
Verification code
Send Inquiry
Verification code
Resources & Supports
Inquiry Basket
loading Loading ......
Delete selectedGo to checkout