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Val-cit-PAB-OH

CAS No.: 159857-79-1

Cat No.: BADC-00708

Purity: 95% 4.5

Val-cit-PAB-OH is a cleavable ADC linker commonly used in targeted therapies. It responds to lysosomal enzymes for selective payload activation in cancer cells.

Val-cit-PAB-OH

Structure of 159857-79-1

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Category

ADC Linker

Molecular Formula

C18H29N5O4

Molecular Weight

379.46

Shipping

-20°C (International: -20°C)

Storage

-20°C

* For research and manufacturing use only. We do not sell to patients.

Size	Price	Stock	Quantity
100 mg	$188	In stock
5 g	$249	In stock

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Capabilities & Facilities

Delivery of 200+ ADCs annually;
mg to g scale for early stage;
4,000 m² cGMP facilities;
CDMO and CMO support.

24/7 customer service;
100% quality assurance;
Efficient global delivery;
Over 95% customer satisfaction.

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Synonyms

L-valyl-N5-carbamoyl-N-[4-(hydroxymethyl)phenyl]-L-omithinamide; Val-cit-PAB; (S)-2-((S)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide

IUPAC Name

(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-(carbamoylamino)-N-[4-(hydroxymethyl)phenyl]pentanamide

Canonical SMILES

CC(C)C(C(=O)NC(CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)N

InChI

InChI=1S/C18H29N5O4/c1-11(2)15(19)17(26)23-14(4-3-9-21-18(20)27)16(25)22-13-7-5-12(10-24)6-8-13/h5-8,11,14-15,24H,3-4,9-10,19H2,1-2H3,(H,22,25)(H,23,26)(H3,20,21,27)/t14-,15-/m0/s1

InChIKey

VEGGTWZUZGZKHY-GJZGRUSLSA-N

Density

1.243±0.06 g/cm3

Solubility

Soluble to ≥ 59 mg/ml in DMSO

Melting Point

715.0±60.0 °C | Condition: Press: 760 Torr

Appearance

White to off-white solid

Quantity

Grams-Kilos

Shelf Life

2 years

Shipping

-20°C (International: -20°C)

Storage

-20°C

Pictograms

Irritant

Signal Word

Warning

Catalog	Product Name	CAS	Inquiry
BADC-01679	Mal-PEG2-Val-Cit-PABA-PNP	1345681-52-8
BADC-00929	Fmoc-D-Val-Cit-PAB	1350456-65-3
BADC-00849	Acetylene-linker-Val-Cit-PABC-MMAE	1411977-95-1
BADC-01448	mDPR-Val-Cit-PAB-MMAE	1491152-26-1
BADC-00958	Amino-PEG4-Val-Cit-PAB-MMAE	1492056-71-9
BADC-00968	MC-Val-Cit-PAB	159857-80-4
BADC-00501	Mc-Val-Cit-PABC-PNP	159857-81-5
BADC-00364	Fmoc-Val-Cit-PAB	159858-22-7
BADC-01348	Val-Cit-PAB-MMAE TFA salt	1608127-32-7
BADC-01745	MC-Val-Cit-PAB-NH-C2-NH-Boc	1616727-22-0

Molarity Calculator
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Historical Records: Nitro-PDS-Tubulysin M | Tubulysin B | Calicheamicin | MMAF Hydrochloride | Fmoc-Val-Cit-PAB | DSP Crosslinker | SPDP | MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH | Boc-Val-Cit-PAB-PNP | Val-Cit | Val-cit-PAB-OH

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