webinar
Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
Read More
  1. Home
  2. Products
  3. ADC Linker
  4. Cleavable Linker
  5. Pyridin-2-yldisulfanyl-PEG4-NHS

Pyridin-2-yldisulfanyl-PEG4-NHS

  CAS No.: 1305053-43-3   Cat No.: BADC-00460   Purity: ≥98% 4.5  

Pyridin-2-yldisulfanyl-PEG4-NHS is a heterobifunctional ADC linker designed for PEGylated, cleavable drug conjugation. The PEG4 spacer improves solubility and flexibility, while the NHS ester and pyridyl disulfide allow for site-specific thiol-reactive coupling in ADC and bioconjugate synthesis.

Pyridin-2-yldisulfanyl-PEG4-NHS

Structure of 1305053-43-3

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support
Category
ADC Linker
Molecular Formula
C20H28N2O8S2
Molecular Weight
488.57
Shipping
Room temperature
Shipping
Store at 2-8°C

* For research and manufacturing use only. We do not sell to patients.

Size Price Stock Quantity
-- $-- In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
Synonyms
PEG4-SPDP; 15-(2-pyridyldithio)-4,7,10,13-tetraoxapentadecanoic acid N-hydroxysuccinimide ester; (2-pyridyldithio)-PEG4-NHS ester; 2,5-dioxopyrrolidin-1-yl 1-(pyridin-2-yldisulfaneyl)-3,6,9,12-tetraoxapentadecan-15-oate; 2,5-dioxo-1-pyrrolidinyl 15-(2-Pyridinyldithio)-4,7,10,13-tetraoxapentadecanoate; 1-{[15-(2-Pyridinyldisulfanyl)-4,7,10,13-tetraoxapentadecan-1-oyl]oxy}-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[[1-oxo-15-(2-pyridinyldithio)-4,7,10,13-tetraoxapentadec-1-yl]oxy]-; 4,7,10,13-Tetraoxapentadecanoic acid, 15-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(pyridin-2-yldisulfanyl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCSSC2=CC=CC=N2
InChI
InChI=1S/C20H28N2O8S2/c23-18-4-5-19(24)22(18)30-20(25)6-8-26-9-10-27-11-12-28-13-14-29-15-16-31-32-17-3-1-2-7-21-17/h1-3,7H,4-6,8-16H2
InChIKey
AZXJOPLHLVNPKQ-UHFFFAOYSA-N
Density
1.3±0.1 g/cm3
Solubility
Soluble in DMSO
Appearance
Colorless to Light Yellow Viscous Liquid
Shipping
Room temperature
Storage
Store at 2-8°C
Boiling Point
605.9±65.0°C at 760 mmHg

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Calculate
The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Calculate

Related Products

Contact our experts today for pricing and comprehensive details on our ADC offerings.

You May Also Be Interested In

From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.

ADC Linker Development Enzyme Cleavable Linker Cathepsin B Cleavable Linker/Peptide Linker Phosphatase Cleavable Linker β-Glucuronide Linker β-Galactosidase Cleavable Linker Sulfatase Cleavable Linker Chemically Cleavable Linker Non-Cleavable Linker Services Acid Cleavable Linker/Hydrazone Linker

Unlock Deeper ADC Insights

Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.

Linkers - A Crucial Factor in Antibody–Drug Conjugates In-Depth Review of ADC Linkers: Types, Mechanisms, and Research Progress New Structural Insights Solve Instability Issues of Maleimide Linkers in ADCs PEG Linkers in Antibody-Drug Conjugates Peptide Linkers in Antibody-Drug Conjugates Disulfide Linkers in Antibody-Drug Conjugates Biotinylation Reagents in Antibody-Drug Conjugates Maleimide Linkers in Antibody-Drug Conjugates Current ADC Linker Chemistry SPDB Linkers in Antibody-Drug Conjugates

Explore More ADC Products

Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.

ADC Cytotoxin

ADC Cytotoxin

Powerful Targeted Cancer Solutions

ADC Cytotoxin with Linker

ADC Cytotoxin with Linker

Enhanced Stability And Efficacy

ADC Linker

ADC Linker

Precise Conjugation For Success

Antibody-Drug Conjugates (ADCs)

Antibody-Drug Conjugates (ADCs)

Maximized Therapeutic Performance

Auristatins

Auristatins

Next-Level Tubulin Inhibition

Calicheamicins

Calicheamicins

High-Impact DNA Targeting

Camptothecins

Camptothecins

Advanced Topoisomerase Inhibition

Daunorubicins / Doxorubicins

Daunorubicins / Doxorubicins

Trusted Anthracycline Payloads

Duocarmycins

Duocarmycins

Potent DNA Alkylation Agents

Maytansinoids

Maytansinoids

Superior Microtubule Disruption

Pyrrolobenzodiazepines

Pyrrolobenzodiazepines

Ultra-Potent DNA Crosslinkers

Traditional Cytotoxic Agents

Traditional Cytotoxic Agents

Proven Chemotherapy Solutions

Cleavable Linker

Cleavable Linker

Precise Intracellular Drug Release

Non-Cleavable Linker

Non-Cleavable Linker

Exceptional Long-Term Stability

Historical Records: MMAE | Amino-ethyl-SS-PEG3-NHBoc | N-Succinimidyl 3-maleimidopropionate | t-boc-N-amido-PEG4-NHS ester | Amino-PEG11-alcohol | Mc-Val-Cit-PABC-PNP | Topotecan | Bis-PEG9-acid | Ducamycin Analog | 6-Azidohexanoic acid NHS ester | Pyridin-2-yldisulfanyl-PEG4-NHS
Send Inquiry
Verification code
Inquiry Basket
loading Loading ......
Delete selectedGo to checkout