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Propargyl-PEG8-acid

  CAS No.: 2055014-94-1   Cat No.: BADC-01035   Purity: ≥95% 4.5  

Propargyl-PEG8-acid features an extended PEG8 spacer for improved solubility and reduced aggregation in ADCs. The alkyne group supports efficient click reactions for covalent drug-antibody linkage in bioconjugation applications.

Propargyl-PEG8-acid

Structure of 2055014-94-1

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Category
ADC Linker
Molecular Formula
C20H36O10
Molecular Weight
436.49
Shipping
Room temperature
Shipping
Store at 2-8°C

* For research and manufacturing use only. We do not sell to patients.

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Synonyms
Alkyne-PEG8-COOH; Propargyl-PEG8-COOH; Propargyl-PEG7-CH2CH2COOH; 4,7,10,13,16,19,22,25-Octaoxaoctacos-27-ynoic acid; 4,7,10,13,16,19,22,25-Octaoxaoctacos-27-yn-1-oic acid
IUPAC Name
3-[2-[2-[2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES
C#CCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
InChI
InChI=1S/C20H36O10/c1-2-4-23-6-8-25-10-12-27-14-16-29-18-19-30-17-15-28-13-11-26-9-7-24-5-3-20(21)22/h1H,3-19H2,(H,21,22)
InChIKey
QZQUQXNQKWZDNM-UHFFFAOYSA-N
Density
1.1±0.1 g/cm3
Solubility
Soluble in DCM, DMF, DMSO, Water
Flash Point
171.9±23.6 °C
Index Of Refraction
1.469
Vapor Pressure
0.0±3.0 mmHg at 25°C
Appearance
Pale Yellow or Colorless Oily Matter
Shelf Life
≥ 2 years
Shipping
Room temperature
Storage
Store at 2-8°C
Boiling Point
531.0±50.0 °C at 760 mmHg
Form
Solid

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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