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Fmoc-GGFG-PAB-OH

  CAS No.: 2632341-89-8   Cat No.: BADC-01456 4.5  

Fmoc-GGFG-PAB-OH is a peptide-based inhibitor that unveils its potential in contributing to the progression of biomedical research and therapeutic interventions. By selectively targeting key enzymes engaged in intricate cellular signaling pathways, this biomedical marvel showcases its prowess in thwarting diseases like cancer, autoimmune disorders, and inflammation.

Fmoc-GGFG-PAB-OH

Structure of 2632341-89-8

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ADC Linker
Molecular Formula
C33H38N4O6
Molecular Weight
586.68

* For research and manufacturing use only. We do not sell to patients.

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Canonical SMILES
O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NC(C(=O)NC(C(=O)NC(C(=O)NC4=CC=C(C=C4)CO)C)C(C)C)C
InChI
InChI=1S/C33H38N4O6/c1-19(2)29(32(41)34-20(3)30(39)36-23-15-13-22(17-38)14-16-23)37-31(40)21(4)35-33(42)43-18-28-26-11-7-5-<br />9-24(26)25-10-6-8-12-27(25)28/h5-16,19-21,28-29,38H,17-18H2,1-4H3,(H,34,41)(H,35,42)(H,36,39)(H,37,40)/t20-,21-,29-/m0/s1
InChIKey
ZQFXTYIBUHTTHZ-WURXVLGASA-N
Density
1.253±0.06 g/cm3
Appearance
White Solid
Boiling Point
911.1±65.0 °C at 760 mmHg

Fmoc-GGFG-PAB-OH, a versatile dipeptide conjugate, finds extensive use in biomedical research and therapeutic development. Here are four key applications of Fmoc-GGFG-PAB-OH:

Drug Delivery Systems: Harnessing the potential of Fmoc-GGFG-PAB-OH, researchers can design prodrugs that lie dormant until reaching their designated target within the body. This dipeptide conjugate serves as a pivotal link between cytotoxic drugs and carriers, ensuring precise delivery to cancer cells. By enhancing therapeutic stability and targeting, it elevates efficacy while diminishing undesirable side effects.

Peptide Synthesis: Within the realm of peptide chemistry, Fmoc-GGFG-PAB-OH acts as a fundamental building block for synthesizing extended peptides and peptide-based bioconjugates. Its integration into peptide structures enables the customization of sequences for diverse research and therapeutic endeavors. The Fmoc-protection group streamlines solid-phase peptide synthesis (SPPS), simplifying the synthesis pathway with finesse.

Immunotherapy Research: Delving into the realm of immunotherapy, Fmoc-GGFG-PAB-OH plays a critical role in crafting peptide-based vaccines and immunomodulatory agents. By tethering immunogenic peptides to carriers using the Fmoc-GGFG-PAB-OH conjugate, researchers can amplify the immune response in experimental models. This innovative strategy is being explored for the development of groundbreaking therapies against infectious diseases and cancer.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: MMAE-[d8] | Fmoc-GGFG-PAB-OH
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