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N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide

  CAS No.: 1225588-29-3   Cat No.: BADC-00532 4.5  

N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide is a fluorinated aldehyde ADC linker that facilitates site-specific antibody conjugation, improving payload stability and antibody-drug conjugate targeting in cancer therapy.

N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide

Structure of 1225588-29-3

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ADC Linker
Molecular Formula
C16H14FNO3
Molecular Weight
287.29
Shipping
Room temperature

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IUPAC Name
N-[2-(3-fluorophenoxy)ethyl]-4-formylbenzamide
Canonical SMILES
C1=CC(=CC(=C1)F)OCCNC(=O)C2=CC=C(C=C2)C=O
InChI
InChI=1S/C16H14FNO3/c17-14-2-1-3-15(10-14)21-9-8-18-16(20)13-6-4-12(11-19)5-7-13/h1-7,10-11H,8-9H2,(H,18,20)
InChIKey
GWDFLSKQRJCFQB-UHFFFAOYSA-N
Shipping
Room temperature

N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide is a compound that has garnered interest in the field of pharmaceutical research due to its potential as a bioactive molecule. One of the primary applications of this compound is in the development of therapeutics targeting inflammatory diseases. Its molecular structure allows it to interact with specific enzymes and receptors that play a crucial role in the inflammatory process. By modulating these interactions, N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide can potentially reduce the expression of pro-inflammatory cytokines, thus providing relief from symptoms associated with chronic inflammation. This property makes it a promising candidate for the treatment of conditions such as rheumatoid arthritis and inflammatory bowel disease.

In addition to its anti-inflammatory potential, N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide has shown promise as an anti-cancer agent. The compound has been studied for its ability to selectively induce apoptosis in cancer cells, sparing normal healthy cells, which is a significant advantage over traditional chemotherapy. This specificity is achieved through its interaction with certain cellular pathways that are often deregulated in cancerous cells. Researchers are particularly interested in its applications in treating breast and lung cancers, where preliminary studies have shown that it can inhibit tumor growth significantly. The development of N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide as a targeted cancer therapy could lead to more effective and less toxic treatment options for patients.

Furthermore, the compound's potential application extends into the realm of neuropharmacology. Recent studies suggest that N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide may have neuroprotective properties. Its ability to cross the blood-brain barrier and modulate neural pathways presents opportunities for developing treatments for neurodegenerative disorders such as Alzheimer's and Parkinson's disease. By reducing oxidative stress and inflammation in neural tissues, this compound could help in preserving cognitive function and slowing the progression of neurodegeneration. These findings offer hope for new therapeutic strategies in managing disorders that currently have limited treatment options.

Finally, N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide is also being explored for its antimicrobial properties. With the rise of antibiotic-resistant strains of bacteria, there is an urgent need for novel antimicrobial agents. This compound has demonstrated inhibitory effects against several pathogenic bacteria, potentially offering a new mechanism of action that could be exploited in antimicrobial drug design. Researchers are optimistic that with further development and clinical trials, N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide could contribute to the next generation of antibiotics, offering safe and effective treatment options for resistant infections.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Aminooxy-PEG3-azide | Gly-Gly-Gly-Gly-OH | Zilovertamab vedotin | Boc-Val-Cit-PABA | 4-Formyl-N-(2-Phenoxyethyl)benzamide | Lycorine hydrochloride | Bis-PEG2-NHS Ester | N-(2-(2-Fluorophenoxy)ethyl)-4-Formylbenzamide | Fmoc-D-Val-D-Cit-PAB | Z-D-Dbu(N3)-OH | N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide
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