N-(2-(2-Chlorophenoxy)ethyl)-4-Formylbenzamide is an aldehyde ADC linker optimized for selective bioorthogonal antibody conjugation. It enhances site-specific drug attachment and targeted payload delivery in ADCs.
Structure of 1225972-65-5
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Potential in Medicinal Chemistry: N-(2-(2-Chlorophenoxy)ethyl)-4-Formylbenzamide is a promising compound in the field of medicinal chemistry, particularly in the development of bioactive molecules. The structure of this compound, featuring the chloro-phenoxy and formylbenzamide functional groups, makes it a valuable scaffold for the synthesis of selective enzyme inhibitors. It is being studied for its potential in targeting a variety of enzymes involved in cellular signaling and disease progression. For example, this compound’s ability to interact with enzymes such as kinases or proteases is being explored for the treatment of diseases like cancer, autoimmune disorders, and inflammation. The reactivity of the formylbenzamide group enhances its potential for modifying key biological pathways, making it a versatile candidate in drug design.
Role in Drug Delivery Systems: N-(2-(2-Chlorophenoxy)ethyl)-4-Formylbenzamide shows great potential in drug delivery systems. The chloro-phenoxyethyl side chain enhances its solubility in both organic and aqueous environments, making it a good candidate for inclusion in nanoparticles, liposomes, or other nanocarriers. These drug delivery systems benefit from the compound's ability to improve stability and control the release of drugs, ensuring more effective targeting of diseased tissues. This makes N-(2-(2-Chlorophenoxy)ethyl)-4-Formylbenzamide particularly useful for treating cancers or other chronic conditions where precision in drug delivery is critical. Additionally, its molecular structure offers flexibility in designing targeted therapies with enhanced bioavailability.
Applications in Protein and Enzyme Inhibition: Another important application of N-(2-(2-Chlorophenoxy)ethyl)-4-Formylbenzamide is in the inhibition of specific proteins or enzymes. The formylbenzamide moiety is known to interact with a variety of biological targets, including protein kinases, which are often dysregulated in diseases like cancer and neurodegenerative disorders. By modifying these proteins, the compound has the potential to either block or regulate their activity, providing a new approach to disease treatment. Researchers are actively investigating its use in high-throughput screening for novel enzyme inhibitors, as it shows promise in modulating enzyme function, thereby offering a pathway for the discovery of new drug candidates.
Contribution to Anti-inflammatory Research: Given its bioactive properties, N-(2-(2-Chlorophenoxy)ethyl)-4-Formylbenzamide is also being explored for its potential in anti-inflammatory research. The compound’s structure is conducive to modulating inflammatory pathways, which are central to the development of diseases such as rheumatoid arthritis, inflammatory bowel disease, and other autoimmune conditions. By interacting with inflammatory mediators, the compound may help in reducing inflammation and tissue damage, offering a new therapeutic angle for these chronic conditions.
Catalog | Product Name | CAS | Inquiry |
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BADC-00523 | N-(2-(2-Chloroethoxy)ethyl)-4-Formylbenzamide | 1137575-49-5 | |
BADC-00531 | N-(2-(4-Fluorophenoxy)ethyl)-4-Formylbenzamide | 1225588-22-6 | |
BADC-00532 | N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide | 1225588-29-3 | |
BADC-00533 | N-(2-(2-Fluorophenoxy)ethyl)-4-Formylbenzamide | 1225705-45-2 | |
BADC-00534 | N-(2-(3-Ethylphenoxy)ethyl)-4-Formylbenzamide | 1225790-49-7 | |
BADC-00535 | N-(2-(4-Ethylphenoxy)ethyl)-4-Formylbenzamide | 1225790-59-9 | |
BADC-00536 | N-(2-(2,6-Dimethylphenoxy)ethyl)-4-Formylbenzamide | 1225936-91-3 | |
BADC-00540 | N-(2-((2,3-Dihydro-1H-Inden-5-yl)oxy)ethyl)-4-Formylbenzamide | 1225979-81-6 | |
BADC-00541 | N-(2-(Benzo[d][1,3]dioxol-5-yloxy)ethyl)-4-Formylbenzamide | 1226006-03-6 | |
BADC-00543 | N-(2-(3-Ethoxyphenoxy)ethyl)-4-Formylbenzamide | 1226006-55-8 |
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