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Ald-Ph-PEG4-bis-PEG3-N3 is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01203 | -- | $-- | Inquiry |
Ald-Ph-PEG4-bis-PEG3-N3 is a bifunctional polyethylene glycol (PEG) reagent useful in various biochemical and medical applications. Here are some key applications of Ald-Ph-PEG4-bis-PEG3-N3:
Bioconjugation: Ald-Ph-PEG4-bis-PEG3-N3 is widely used in bioconjugation to link proteins, peptides, or other biomolecules for therapeutic and diagnostic purposes. Its bifunctional nature allows for efficient crosslinking and attachment to different biomolecules. This enhances the stability, solubility, and efficacy of the conjugated molecules in biomedical applications.
Drug Delivery: In drug delivery systems, Ald-Ph-PEG4-bis-PEG3-N3 can be used to modify the surface of nanoparticles or drug carriers. By attaching this reagent, properties such as biocompatibility and circulation time in the bloodstream can be improved. This leads to more effective targeting and controlled release of therapeutic agents.
Surface Modification: Ald-Ph-PEG4-bis-PEG3-N3 is useful for the modification of surfaces in biosensors and medical devices. By coating surfaces with this PEG reagent, nonspecific binding of proteins and cells can be minimized. This results in higher sensitivity and specificity of diagnostic assays and reduces the risk of biofouling in medical implants.
Protein Stabilization: In protein research, Ald-Ph-PEG4-bis-PEG3-N3 is employed to increase the stability and solubility of recombinant proteins. Conjugating proteins with this reagent can prevent aggregation and enhance their functional properties. This is particularly important for the production and storage of therapeutic proteins and enzymes.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
