Events
Meet BOC Sciences at AAPS PharmSci 360 2026 — Booth #811
Oct. 25–28, 2026, New Orleans, LA
Register

6-Azido-hexylamine

  Cat No.: BADC-01527   Purity: >95% 4.5  

6-Azido-hexylamine is a bioorthogonal conjugation building block that provides an azide handle for modular click-chemistry workflows. The molecule can be used to introduce a click-reactive group onto an antibody, peptide, linker intermediate, or payload-containing component, depending on the chemistry of its second terminal functionality. Its additional reactive group is azide bioorthogonal handle; requires complementary click handle on the antibody. Conjugation can be performed using spaac with dbco/bcn-functionalized partner or cuaac with terminal alkyne partner, depending the complementary handle. The sequence and orientation of the coupling steps should be selected according to the functional groups carried by the two conjugation partners.

6-Azido-hexylamine

Structure of 349553-73-7

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support
Category
ADC Linker
Molecular Formula
C6H14N4
Molecular Weight
142.20

* For research and manufacturing use only. We do not sell to patients.

Size Price Stock Quantity
-- $-- In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
Synonyms
6-azidohexan-1-amine; 6-AZIDO-HEXYLAMINE; 6-Azido-1-hexanamine; 6-azidohexylamine; 6-Azido-1-hexaneamine
IUPAC Name
6-azidohexan-1-amine
SMILES
C(CCCN=[N+]=[N-])CCN
InChI
InChI=1S/C6H14N4/c7-5-3-1-2-4-6-9-10-8/h1-7H2
InChIKey
CLQMAUAPICAWGT-UHFFFAOYSA-N
Pictograms
Flammable; Corrosive
Signal Word
Danger

6-Azido-hexylamine, a versatile chemical compound, plays a pivotal role in bioconjugation, molecular biology, and materials science. Here are four key applications of 6-Azido-hexylamine presented with a high degree of perplexity and burstiness:

Bioconjugation: Serving as a linchpin in click chemistry, 6-Azido-hexylamine is a go-to compound for bioconjugation of biomolecules. Its azide group selectively reacts with alkynes in a copper-catalyzed dance, paving the way for attaching diverse probes, drugs, or fluorophores to proteins, nucleic acids, or other biomolecules. This intricate process allows for the precise tracking, imaging, and functionalization of biological targets, opening new vistas for intricate molecular manipulations.

Drug Delivery: In the realm of drug delivery research, 6-Azido-hexylamine emerges as a stalwart, aiding in the modification of drug carriers such as liposomes, nanoparticles, and polymers. By forming a stable azide-alkyne union, therapeutic molecules can be securely tethered to these carriers, ensuring controlled and targeted drug release mechanisms. This strategic maneuver not only enhances treatment efficacy and safety by guiding drugs to specific cells or tissues but also underscores the finesse involved in pharmaceutical interventions.

Materials Science: Unleashing its prowess in materials science, 6-Azido-hexylamine assumes a central role in surface functionalization and material development with tailored properties. By wielding its transformative touch on nanoparticle surfaces, this compound engineers materials boasting bespoke chemical and physical characteristics. This artistry finds resonance in the creation of advanced materials catering to diverse applications in catalysis, sensor technologies, and nano-engineering, marking a renaissance in material innovations.

Molecular Biology: In the intricate realm of molecular biology, 6-Azido-hexylamine emerges as a beacon, particularly in crafting labeled DNA and RNA probes. By incorporating the azido group into nucleic acid sequences, it lays the groundwork for attaching fluorescent dyes or other detection molecules through the elegant choreography of click chemistry. This synergy is indispensable for a myriad of assays, including the intricate dance of fluorescence in situ hybridization (FISH) and other nucleic acid-based detection methodologies, painting a vivid canvas of molecular intricacies.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Contact our experts today for pricing and comprehensive details on our ADC offerings.

You May Also Be Interested In

From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.

ADC Linker Development Enzyme Cleavable Linker Cathepsin B Cleavable Linker Phosphatase Cleavable Linker β-Glucuronide Linker β-Galactosidase Cleavable Linker Sulfatase Cleavable Linker Chemically Cleavable Linker Non-Cleavable Linker Services Acid Cleavable Linker

Unlock Deeper ADC Insights

Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.

Linkers - A Crucial Factor in Antibody–Drug Conjugates In-Depth Review of ADC Linkers: Types, Mechanisms, and Research Progress New Structural Insights Solve Instability Issues of Maleimide Linkers in ADCs PEG Linkers in Antibody-Drug Conjugates Peptide Linkers in Antibody-Drug Conjugates Disulfide Linkers in Antibody-Drug Conjugates Biotinylation Reagents in Antibody-Drug Conjugates Maleimide Linkers in Antibody-Drug Conjugates Current ADC Linker Chemistry SPDB Linkers in Antibody-Drug Conjugates

Explore More ADC Products

Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.

ADC Cytotoxin

Powerful Targeted Cancer Solutions

ADC  Cytotoxin with Linker

Enhanced Stability And Efficacy

ADC Linker

Precise Conjugation For Success

Antibody-Drug  Conjugates (ADCs)

Maximized Therapeutic Performance

Auristatins

Next-Level Tubulin Inhibition

Calicheamicins

High-Impact DNA Targeting

Camptothecins

Advanced Topoisomerase Inhibition

Daunorubicins / Doxorubicins

Trusted Anthracycline Payloads

Duocarmycins

Potent DNA Alkylation Agents

Maytansinoids

Superior Microtubule Disruption

Pyrrolobenzodiazepines

Ultra-Potent DNA Crosslinkers

Traditional Cytotoxic Agents

Proven Chemotherapy Solutions

Cleavable Linker

Precise Intracellular Drug Release

Non-Cleavable Linker

Exceptional Long-Term Stability

Historical Records: Oportuzumab monatox | Patritumab deruxtecan | Anetumab ravtansine | Lorvotuzumab mertansine | Mc-VC-PAB-SN38 | Docosanedioic acid | Isofistularin-3 | Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP | Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc | Irinotecan EP Impurity E (SN-38) | 6-Azido-hexylamine
Send Inquiry
Verification code
Inquiry Basket
Loading Loading......
Go to checkout