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CAS No.: 111625-28-6
Cat No.: BADC-00891
Purity: >98%
4.5 
(2-pyridyldithio)-PEG1-hydrazine is a cleavable ADC linker featuring pyridyl disulfide and hydrazine groups. It facilitates thiol-reactive conjugation and hydrazone chemistry for pH-sensitive payload release in ADC development.
Structure of 111625-28-6
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(2-pyridyldithio)-PEG1-hydrazine, a versatile bifunctional crosslinker, plays a pivotal role in biochemical and pharmaceutical research. Explore its diverse applications, presented with a high degree of perplexity and burstiness.
Protein Conjugation: By harnessing the power of (2-pyridyldithio)-PEG1-hydrazine, scientists intricately link proteins to various molecules or surfaces, creating enduring protein conjugates essential for crafting tailored antibody-drug conjugates (ADCs) for precise cancer therapy. The unique bifunctional nature of this molecule seamlessly attaches to thiol and carbonyl groups, facilitating precise conjugation with unparalleled precision.
Biomolecule Labeling: In the depths of biomolecular research, researchers utilize (2-pyridyldithio)-PEG1-hydrazine for precise labeling of proteins, peptides, or biomolecules with vibrant fluorescent dyes or innovative probes. By selectively reacting with thiol groups, this reagent ensures specific and efficient labeling, enabling detailed studies of biomolecular interactions and cellular processes under the revealing lens of a fluorescence microscope.
Drug Delivery Systems: Venturing into the innovative world of drug delivery, (2-pyridyldithio)-PEG1-hydrazine emerges as a key player in modifying nanoparticles or liposomes with targeted ligands to enhance drug delivery systems. This molecular modification enhances specificity and efficacy, guiding therapeutic agents precisely to designated tissues or cells. With the hydrazine group forming stable bonds under physiological conditions, controlled release of therapeutic agents is assured, revolutionizing drug delivery strategies.
Enzyme Immobilization: In the realm of biosensors and industrial biocatalysis, (2-pyridyldithio)-PEG1-hydrazine serves as a critical tool for immobilizing enzymes onto solid supports. This strategic conjugation not only maintains enzyme activity but also provides a robust attachment to diverse surfaces, enabling the creation of reusable biocatalysts and elevating the efficiency of biochemical assays to new heights of precision and reliability.
| Catalog | Product Name | CAS | Inquiry |
|---|---|---|---|
| BADC-01141 | (2-pyridyldithio)-PEG4 acid | 581065-93-2 | |
| BADC-01522 | (2-Pyridyldithio)-PEG6 acid |
(2-pyridyldithio)-PEG1-hydrazine
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(2-pyridyldithio)-PEG1-hydrazine
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