Name: (2-Pyridyldithio)-PEG6 acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

Synonyms

(2-Pyridyldithio)-PEG6 acid

IUPAC Name

Canonical SMILES

C1=CC=NC(=C1)SSCCOCCOCCOCCOCCOCCOCCC(=O)O

InChI

InChI=1S/C20H33NO8S2/c22-20(23)4-6-24-7-8-25-9-10-26-11-12-27-13-14-28-15-16-29-17-18-30-31-19-3-1-2-5-21-19/h1-3,5H,4,6-18H2,(H,22,23)

InChIKey

JTOIKSHNFJXKKI-UHFFFAOYSA-N

(2-Pyridyldithio)-PEG6 acid, a versatile linker in bioconjugation, plays a crucial role in connecting biomolecules for diverse research and therapeutic purposes. Exploring its key applications with heightened perplexity and burstiness:

Antibody-Drug Conjugates: A cornerstone in cancer treatment innovation, (2-Pyridyldithio)-PEG6 acid forms enduring linkages between antibodies and cytotoxic drugs, pivotal in crafting antibody-drug conjugates (ADCs). These conjugates revolutionize chemotherapy by targeting cancer cells directly, reducing systemic toxicity, and elevating the efficacy of anticancer therapies, ultimately advancing patient outcomes.

Protein Labeling: In the realm of protein research, scientists leverage (2-Pyridyldithio)-PEG6 acid to affix fluorescent probes or other tags to proteins, enabling visualization and tracking for a profound understanding of protein dynamics and interactions within cellular environments. Through precise labeling, researchers unravel intricate cellular processes and unveil the nuances of protein functionality with heightened clarity.

Drug Delivery Systems: At the forefront of drug delivery advancements, (2-Pyridyldithio)-PEG6 acid plays an instrumental role in designing targeted drug delivery systems. By conjugating therapeutic molecules to carriers like liposomes or nanoparticles, this compound enhances the efficient delivery of drugs to specific tissues or cells, amplifying therapeutic effects and minimizing adverse reactions. The PEG component further enhances solubility and biocompatibility, optimizing the performance of these advanced delivery platforms.

Biological Assays: In the domain of biological assays, (2-Pyridyldithio)-PEG6 acid serves as a fundamental tool for anchoring biomolecules onto surfaces in diagnostic tests, biosensors, and high-throughput screening assays. This immobilization step is critical for functional assays, and the PEG spacer provides flexibility while reducing steric hindrance, ensuring the optimal activity of attached biomolecules and enabling precise and reliable biological analyses.