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(2S,2'S)-Bis(2,5-dioxopyrrolidin-1-Yl) 4,4'-disulfanediylbis(2-(((benzyloxy)carbonyl)amino)butanoate) is a linker for antibody-drug-conjugation (ADC).
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-00676 | -- | $-- | Inquiry |
(2S,2'S)-Bis(2,5-dioxopyrrolidin-1-yl)-4,4'-disulfanediylbis(2-(((benzyloxy)carbonyl)amino)butanoate) is a versatile reagent commonly deployed in peptide synthesis and biochemical research. Here are four key applications of this compound presented with a high degree of perplexity and burstiness:
Peptide Synthesis: This compound serves as a coupling reagent in solid-phase peptide synthesis, excelling in the formation of peptide bonds. Its efficiency is instrumental in peptide and small protein creation, wielding importance in research and pharmaceutical realms. By catalyzing swift and high-yielding amide bond formation, it simplifies the synthetic process, enhancing productivity and precision.
Protein Cross-Linking: Employed for generating stable cross-links between protein entities, this compound is paramount for exploring protein-protein interactions, structural biology, and protein complex stabilization. This function is pivotal in unraveling the interconnected roles of diverse proteins, aiding in therapeutic innovation and biomedical research endeavors.
Affinity Chromatography: Within biochemical investigations, this compound finds utility in modifying affinity chromatography resins. By binding selectively to the resin, it enhances the purification process by targeting specific molecules, refining the specificity and efficiency of protein isolation. This advancement elevates the capacity to extract and analyze proteins within intricate biological mixtures, enhancing research capabilities.
Drug Delivery Systems: This compound plays a critical role in crafting drug delivery systems, enabling modifications to drug carriers and drug conjugation to targeting components. It contributes to the development of robust and biocompatible linkers, leading to controlled drug release at designated sites. Such precision in drug delivery not only heightens efficacy but also mitigates side effects, ensuring accurate drug deployment and release mechanisms.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
