Sibiromycin - CAS 12684-33-2

Sibiromycin - CAS 12684-33-2 Catalog number: BADC-00796

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

It is an aminoglycoside antibiotic produced by the strain of Streptosporangium sibiricum. It has anti-bacterial effect and has an inhibitory effect on reticuloendothelial sarcoma RAB-1 and oncogenic AK/LY cells. Two times of the maximum tolerated dose of intravenous administration can inhibit OZH-5 tumor and lymphosarcoma Lic-1. It has very high DNA binding affinity and cytotoxicity against cancer cell lines.

General Information

Category
ADCs Cytotoxin
Product Name
Sibiromycin
CAS
12684-33-2
Catalog Number
BADC-00796
Molecular Formula
C24H33N3O7
Molecular Weight
475.54

Chemical Structure

  • Sibiromycin
Appearance
Creaminess
Synonyms
Sybiromycin; 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 7-((4,6-dideoxy-3-C-methyl-4-(methylamino)-alpha-L-mannopyranosyl)oxy)-1,10,11,11a-treahydro-9,11-dihydroxy-8-methyl-2-(1E)-1-propenyl-, (11R,11aS)-
Solubility
Soluble in Methanol, Dimethylformamide
Storage
Store at-20°C
Boiling Point
755.7°C at 760 mmHg
Melting Point
>120°C (dec.)
Density
1.41 g/cm3
Canonical SMILES
CC=CC1=CN2C(C1)C(NC3=C(C(=C(C=C3C2=O)OC4C(C(C(C(O4)C)NC)(C)O)O)C)O)O
InChI Key
RAGFPHFDFVNLCG-INYQBOQCSA-N
InChI
InChI=1S/C24H33N3O7/c1-6-7-13-8-15-21(30)26-17-14(22(31)27(15)10-13)9-16(11(2)18(17)28)34-23-20(29)24(4,32)19(25-5)12(3)33-23/h6-7,9-10,12,15,19-21,23,25-26,28-30,32H,8H2,1-5H3/b7-6+/t12-,15-,19-,20-,21+,23-,24+/m0/s1

Related Products

Get in Touch

Verification code
Inquiry Basket