7-MAD-MDCPT - CAS 765871-81-6
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7-MAD-MDCPT - CAS 765871-81-6 Catalog number: BADC-01479

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7-MAD-MDCPT, a camptothecin analog, is the active moiety in an antibody drug conjugate (ADC).

Category
ADCs Cytotoxin
Product Name
7-MAD-MDCPT
CAS
765871-81-6
Catalog Number
BADC-01479
Molecular Formula
C22H19N3O6
Molecular Weight
421.40
7-MAD-MDCPT

Ordering Information

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Other Types of Cytotoxins
Auristatins Calicheamicins Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Piericidins Pyrrolobenzodiazepines Traditional Cytotoxic Agents Others
Description
7-MAD-MDCPT, a camptothecin analog, is the active moiety in an antibody drug conjugate (ADC).
Synonyms
7-MAD-MDCPT; (S)-14-(Aminomethyl)-7-ethyl-7-hydroxy-7H-[1,3]dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(10H,13H)-dione
IUPAC Name
(5S)-14-(aminomethyl)-5-ethyl-5-hydroxy-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.04,9.015,23.017,21]tetracosa-1(24),2,4(9),13,15,17(21),22-heptaene-6,10-dione
Canonical SMILES
CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC6=C(C=C5N=C4C3=C2)OCO6)CN)O
InChI
InChI=1S/C22H19N3O6/c1-2-22(28)14-4-16-19-12(7-25(16)20(26)13(14)8-29-21(22)27)11(6-23)10-3-17-18(31-9-30-17)5-15(10)24-19/h3-5,28H,2,6-9,23H2,1H3/t22-/m0/s1
InChIKey
QILNNZJGRYNYJV-QFIPXVFZSA-N
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: MCC | Sudemycin C | Nα-Azido-Nβ-Boc-L-2,3-diaminopropionic acid | Boc-D-Orn(N3)-OH (CHA) | m-PEG12-OH | 7-MAD-MDCPT
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