Name: 6-Azidohexanoic acid NHS ester
Brand: BOC Sciences
Price: 1099 USD
Availability: MadeToOrder

Synonyms

N3-C5-NHS ester

IUPAC Name

(2,5-dioxopyrrolidin-1-yl) 6-azidohexanoate

Canonical SMILES

C1CC(=O)N(C1=O)OC(=O)CCCCCN=[N+]=[N-]

InChI

InChI=1S/C10H14N4O4/c11-13-12-7-3-1-2-4-10(17)18-14-8(15)5-6-9(14)16/h1-7H2

InChIKey

FVWGCTQOFSJEDB-UHFFFAOYSA-N

Appearance

Slightly yellow oil

Shipping

Room temperature, or blue ice upon request.

Storage

Store at -20 °C, desiccate and shipped at ambient temperature

6-Azidohexanoic acid NHS ester, a versatile reagent widely utilized in bioconjugation and chemical biology, is a key player in various applications. Here we explore its diverse uses with a twist of high perplexity and burstiness.

Protein Labeling: Enter the realm of protein modification with 6-Azidohexanoic acid NHS ester, the magic wand that covalently links azide groups to proteins through click chemistry. This innovative technique allows for the seamless labeling and monitoring of proteins using fluorescent probes or affinity tags. Witness these conjugated proteins in action, illuminating assays like fluorescence microscopy and Western blotting with their dynamic presence.

Peptide Synthesis: Embark on a journey through peptide synthesis where 6-Azidohexanoic acid NHS ester reigns supreme in incorporating azide functionality into peptides. These azide-modified peptides pave the way for click chemistry reactions, forming peptide conjugates with biomolecules like PEG chains or drugs. Dive into the world of peptide-based therapeutics and delivery systems, where this strategy orchestrates intricate molecular dances for therapeutic advancements.

Nanoparticle Functionalization: Behold the transformative powers of 6-Azidohexanoic acid NHS ester in nanoparticle functionalization, where azide groups bring forth endless possibilities through click chemistry. Witness the evolution of functionalized nanoparticles as they partner with targeting ligands, drugs, or imaging agents. Experience the birth of targeted drug delivery systems and diagnostic imaging tools where precision meets innovation in the realm of healthcare advancements.

Surface Immobilization: Step into the realm of surface engineering with 6-Azidohexanoic acid NHS ester as it paints surfaces with azide groups, like an artist creating a masterpiece. Watch as these azide-functionalized surfaces come to life, ready to host biomolecules through click chemistry, birthing bioactive surfaces for biosensors and cell culture substrates. Explore the realm of advanced biosensors and biointerfaces, where the language of molecular interactions unfolds, shaping the future of diagnostic and research endeavors.