Name: MP-PEG4-VK(Boc)G-OSu
Brand: BOC Sciences
Rating: 5 (1 reviews)

Synonyms

MP-PEG4-VK(Boc)G-Osu

IUPAC Name

(2,5-dioxopyrrolidin-1-yl) 2-[[(2S)-2-[[(2S)-2-[3-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-methylbutanoyl]amino]-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoyl]amino]acetate

Canonical SMILES

CC(C)C(C(=O)NC(CCCCNC(=O)OC(C)(C)C)C(=O)NCC(=O)ON1C(=O)CCC1=O)NC(=O)CCOCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O

InChI

InChI=1S/C40H63N7O16/c1-27(2)36(45-30(49)14-18-58-20-22-60-24-25-61-23-21-59-19-16-41-29(48)13-17-46-31(50)9-10-32(46)51)38(56)44-28(8-6-7-15-42-39(57)62-40(3,4)5)37(55)43-26-35(54)63-47-33(52)11-12-34(47)53/h9-10,27-28,36H,6-8,11-26H2,1-5H3,(H,41,48)(H,42,57)(H,43,55)(H,44,56)(H,45,49)/t28-,36-/m0/s1

InChIKey

PACRZKFVWJUBCK-GOOPYHEFSA-N

MP-PEG4-VK(Boc)G-OSu, a cutting-edge chemical compound in bioconjugation and drug development, offers a plethora of applications.

Bioconjugation: MP-PEG4-VK(Boc)G-OSu serves as a versatile instrument for conjugating proteins, peptides, and a myriad of biomolecules. Featuring an N-hydroxysuccinimide (NHS) ester group, it facilitates the formation of stable amide bonds with primary amines, a prevalent feature in proteins and peptides. This modification not only enhances the solubility and stability of the conjugated entities but also augments their bioavailability, unveiling novel avenues for research and development.

Drug Delivery Systems: Spearheading innovation in drug delivery, MP-PEG4-VK(Boc)G-OSu assumes a pivotal role in crafting sophisticated delivery systems. It is harnessed to append polyethylene glycol (PEG) chains to therapeutic molecules through PEGylation. This alteration amplifies the pharmacokinetics of drugs by mitigating immunogenicity and prolonging circulation time in the bloodstream.

Material Science: Within the realm of material science, MP-PEG4-VK(Boc)G-OSu finds utility in surface and nanoparticle functionalization, modifying their properties. This contribution bolsters biocompatibility and averts nonspecific binding in biomedical tools and diagnostic assays. The compound's role in augmenting the performance of medical implants and biosensors via surface enhancements underscores its significance in propelling healthcare technologies and elevating patient outcomes.

Proteomics Research: In the dynamic landscape of proteomics, MP-PEG4-VK(Boc)G-OSu emerges as an indispensable asset for labeling proteins in diverse analytical methodologies, including mass spectrometry. Its distinct functional groups enable precise tagging, facilitating specific identification and quantification of proteins within complex mixtures.