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MP-PEG8-VA-PABC is a biomedical product used for targeted drug delivery in cancer treatment. With its polyethylene glycol (PEG) and maleimide functional groups, it efficiently conjugates to antibodies or therapeutic agents, enabling precise and controlled release at the tumor site. It shows potential in treating various types of cancers, including breast, lung, and prostate cancer.
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01491 | -- | $-- | Inquiry |
MP-PEG8-VA-PABC, a multifunctional linker crucial in the advancement of cutting-edge drug delivery systems, boasts a myriad of applications.
Targeted Drug Delivery: MP-PEG8-VA-PABC plays a pivotal role in crafting targeted drug delivery vehicles that ferry therapeutics directly to ailing cells or tissues. By coupling this linker with drugs and targeting moieties, researchers adeptly enhance drug uptake by specific cells, especially cancer cells. This tailored strategy curtails off-target effects, amplifying the potency of treatments.
Prodrug Design: MP-PEG8-VA-PABC emerges as a crucial spacer and triggerable linker, governing the union between the active pharmaceutical ingredient (API) and the aiming entity. The strategic use of this linker permits controlled release of the API upon reaching the designated site, ensuring drug activation solely at the requisite location.
Bioconjugation: Within the domain of bioconjugation processes, MP-PEG8-VA-PABC acts as a linchpin, bridging biologically active molecules like peptides or antibodies to polymers or diverse compounds. This linkage begets bioconjugates endowed with heightened stability, solubility, and bioavailability, pivotal in crafting diagnostic tools and avant-garde therapeutic agents.
Complex Drug Formulation: Pioneering complex drug formulations, MP-PEG8-VA-PABC orchestrates the union of multiple therapeutic agents within a unified delivery framework. This innovation enables the concurrent dispensation of diverse drugs with synergistic impacts against ailments such as cancer and infectious diseases. By harnessing such formulations, researchers steer toward enhanced therapeutic efficacy and surmounting drug resistance.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
