Spliceostatin A - CAS 391611-36-2

Spliceostatin A - CAS 391611-36-2 Catalog number: BADC-00780

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a potent pre-mRNA splicing inhibitor.Spliceostatin A is a methylated and more stable derivative of FR901464. Spliceostatin A show a similar activity with FR901464.

General Information

Category
ADCs Cytotoxin
Product Name
Spliceostatin A
CAS
391611-36-2
Catalog Number
BADC-00780
Molecular Formula
C28H43NO8
Molecular Weight
521.65

Chemical Structure

  • Spliceostatin A
Synonyms
[(Z,2S)-4-[[(2R,3R,5S,6S)-6-[(2E,4E)-5-[(3R,4R,5R,7S)-4-hydroxy-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl]-3-methylpenta-2,4-dienyl]-2,5-dimethyloxan-3-yl]carbamoyl]but-3-en-2-yl] acetate; (2Z,4S)-N-[(2R,3R,5S,6S)-2,5-Dimethyl-6-[(2E)-3-methyl-5-[(3R,4R,5R,7S)-4-hydroxy-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]octane-5-yl]-2,4-pentadienyl]tetrahydro-2H-pyran-3-yl]-4-acetoxy-2-penteneamide
Storage
-20°C
Canonical SMILES
CC1CC(C(OC1CC=C(C)C=CC2C(C3(CC(O2)(C)OC)CO3)O)C)NC(=O)C=CC(C)OC(=O)C
InChI Key
XKSGIJNRMWHQIQ-CGPJBNNXSA-N
InChI
InChI=1S/C28H43NO8/c1-17(9-12-24-26(32)28(16-34-28)15-27(6,33-7)37-24)8-11-23-18(2)14-22(20(4)36-23)29-25(31)13-10-19(3)35-21(5)30/h8-10,12-13,18-20,22-24,26,32H,11,14-16H2,1-7H3,(H,29,31)/b12-9+,13-10-,17-8+/t18-,19-,20+,22+,23-,24+,26+,27-,28+/m0/s1

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