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Methyltetrazine-PEG4-oxyamine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01289 | -- | $-- | Inquiry |
Methyltetrazine-PEG4-oxyamine, a versatile bifunctional chemical compound, is a prominent player in bioconjugation and labeling techniques. Let's explore the diverse applications of Methyltetrazine-PEG4-oxyamine with intricacy and dynamism:
Bioconjugation: At the forefront of bioconjugation, Methyltetrazine-PEG4-oxyamine shines brightly thanks to its rapid reactivity with tetrazine-reactive groups through bioorthogonal click chemistry. This seamless reaction offers an efficient avenue for labeling biomolecules like proteins and antibodies, preserving their native functionality. The PEG4 spacer adds a touch of flexibility, enhancing solubility and reducing steric hindrance during conjugation.
In Vivo Imaging: Delving into in vivo imaging, Methyltetrazine-PEG4-oxyamine emerges as a vital component, linking imaging agents to biomolecules for real-time investigations of biological phenomena. The swift and selective bonding between Methyltetrazine-PEG4-oxyamine and tetrazine-modified probes ensures stable and specific labeling. This cutting-edge technology elevates target detection in live cells or animal models, propelling advancements in research, diagnosis, and therapeutic tracking.
Drug Delivery Systems: Driving innovation in targeted drug delivery, Methyltetrazine-PEG4-oxyamine takes center stage by facilitating the development of precise drug delivery systems. By conjugating therapeutic agents to targeting molecules, this compound enables efficient and selective drug delivery to specific tissues or cells. This tailored approach minimizes off-target effects and amplifies treatment efficacy, ensuring drugs are activated precisely where needed.
Protein Cross-Linking: In the realm of protein chemistry, Methyltetrazine-PEG4-oxyamine serves a critical role in protein cross-linking, pivotal for exploring protein-protein interactions. This compound fosters the creation of robust covalent bonds between diverse protein entities, preserving intricate structures for in-depth analysis.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
