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Mc-MMAD - CAS 1401963-15-2 Catalog number: BADC-00026
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Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate; Mc-MMAD is a protective group (maleimidocaproyl) -conjugated MMAD.
Category
ADCs Cytotoxin
Product Name
Mc-MMAD
CAS
1401963-15-2
Catalog Number
BADC-00026
Molecular Formula
C51H77N7O9S
Molecular Weight
964.26
Ordering Information
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00026 | -- | $-- |
Description
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate; Mc-MMAD is a protective group (maleimidocaproyl) -conjugated MMAD.
Synonyms
Mc MMAD; McMMAD
IUPAC Name
6-(2,5-dioxopyrrol-1-yl)-N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-3-methoxy-1-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino]propyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylhexanamide
Canonical SMILES
CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C3=NC=CS3)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C(=O)CCCCCN4C(=O)C=CC4=O
InChI
InChI=1S/C51H77N7O9S/c1-12-34(6)46(56(9)51(65)44(32(2)3)54-49(64)45(33(4)5)55(8)40(59)23-17-14-18-27-58-41(60)24-25-42(58)61)39(66-10)31-43(62)57-28-19-22-38(57)47(67-11)35(7)48(63)53-37(50-52-26-29-68-50)30-36-20-15-13-16-21-36/h13,15-16,20-21,24-26,29,32-35,37-39,44-47H,12,14,17-19,22-23,27-28,30-31H2,1-11H3,(H,53,63)(H,54,64)/t34-,35+,37-,38-,39+,44-,45-,46-,47+/m0/s1
InChIKey
OZUQLKHIIRUJRZ-PGBUMTRMSA-N
Application
ADCs Cytotoxin-Linker
Appearance
Solid Power
Purity
>98%
Shelf Life
≥360 days if stored properly
Shipping
Room temperature
Related Products
Historical Records: DOXO-EMCH | Tubulysin B | Mensacarcin | 17-AEP-GA | DM4-SPDP | AcLysValCit-PABC-DMAE-SW-163D | DBCO-(PEG2-VC-PAB-MMAE)2 | Fmoc-Val-Ala-PAB-PNP | Lys-SMCC-DM1 | Topotecan | Mc-MMAD
