Biotin-MeTZ - CAS 1802883-51-7

Biotin-MeTZ - CAS 1802883-51-7 Catalog number: BADC-01800

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Biotin-MeTz shiyi is a click chemistry reagent with a terminal methyltetrazine group.

Category
ADCs Linker
Product Name
Biotin-MeTZ
CAS
1802883-51-7
Catalog Number
BADC-01800
Molecular Formula
C20H25N7O2S
Molecular Weight
427.52

Ordering Information

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BADC-01800 -- $--
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Description
Biotin-MeTz shiyi is a click chemistry reagent with a terminal methyltetrazine group.
IUPAC Name
5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]methyl]pentanamide
Canonical SMILES
CC1=NN=C(N=N1)C2=CC=C(C=C2)CNC(=O)CCCCC3C4C(CS3)NC(=O)N4
InChI
InChI=1S/C20H25N7O2S/c1-12-24-26-19(27-25-12)14-8-6-13(7-9-14)10-21-17(28)5-3-2-4-16-18-15(11-30-16)22-20(29)23-18/h6-9,15-16,18H,2-5,10-11H2,1H3,(H,21,28)(H2,22,23,29)/t15-,16-,18-/m0/s1
InChIKey
CYKMCHSUZVIUJZ-BQFCYCMXSA-N

Biotin-MeTZ, a potent biotin derivative, plays a pivotal role in diverse bioscience applications. Here are four key applications of Biotin-MeTZ presented with high perplexity and burstiness:

Protein Labeling: Widely employed for protein labeling, Biotin-MeTZ boasts a strong affinity for avidin and streptavidin. Through covalent attachment to proteins, researchers can effectively capture and detect these proteins within intricate biological samples. This application is indispensable for protein purification, identification, and quantification across a myriad of experimental settings, elevating the precision and depth of protein analysis.

Immunoassays: In the realm of immunoassays, Biotin-MeTZ emerges as a potent enhancer of sensitivity and specificity in detection methodologies. Whether conjugated to antibodies or antigens, Biotin-MeTZ facilitates their binding to streptavidin-coated surfaces, enhancing assay performance. This refinement benefits assays like ELISA and western blotting, augmenting result accuracy and reliability, thereby facilitating advanced biomolecular analysis.

Cell Surface Studies: Through cell surface labeling, Biotin-MeTZ enables the exploration of cell surface dynamics and interactions. By tagging cell surface molecules with Biotin-MeTZ, researchers can effectively isolate or track cells using streptavidin-based techniques. This capability proves particularly valuable in flow cytometry and cell sorting applications, enabling in-depth analysis of cell populations and their unique characteristics, shedding light on cellular behaviors.

Diagnostics: A cornerstone of diagnostic platforms, Biotin-MeTZ plays a critical role in the detection of specific biomolecules. Whether in diagnostic tests for infections or genetic disorders, the conjugation of Biotin-MeTZ to probes or primers enhances signal detection, elevating test sensitivity and accuracy. This application transforms disease diagnosis and monitoring, offering heightened precision and reliability in detecting biomarkers essential for effective healthcare management.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: N3-D-Orn(Boc)-OH
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