SG3199 - CAS 1595275-71-0

SG3199 - CAS 1595275-71-0 Catalog number: BADC-01353

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SG3199 is a cytotoxic DNA minor groove interchain cross-linked PDB dimer. SG3199 is a component of ADC payload Tesirine (SG3249).

Category
ADCs Cytotoxin
Product Name
SG3199
CAS
1595275-71-0
Catalog Number
BADC-01353
Molecular Formula
C33H36N4O6
Molecular Weight
584.66
Purity
95.46%
SG3199

Ordering Information

Catalog Number Size Price Quantity
BADC-01353 -- $-- Inquiry
Description
SG3199 is a cytotoxic DNA minor groove interchain cross-linked PDB dimer. SG3199 is a component of ADC payload Tesirine (SG3249).
Synonyms
SG-3199; (11aS,11a'S)-8,8'-(Pentane-1,5-diylbis(oxy))bis(7-methoxy-2-methyl-1,11a-dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5-one)
IUPAC Name
3-[5-[[(6aR)-2-methoxy-8-methyl-11-oxo-6a,7-dihydropyrrolo[2,1-c][1,4]benzodiazepin-3-yl]oxy]pentoxy]-2-methoxy-8-methyl-6a,7-dihydropyrrolo[2,1-c][1,4]benzodiazepin-11-one
Canonical SMILES
CC1=CN2C(C1)C=NC3=CC(=C(C=C3C2=O)OC)OCCCCCOC4=C(C=C5C(=C4)N=CC6CC(=CN6C5=O)C)OC
InChI
InChI=1S/C33H36N4O6/c1-20-10-22-16-34-26-14-30(28(40-3)12-24(26)32(38)36(22)18-20)42-8-6-5-7-9-43-31-15-27-25(13-29(31)41-4)33(39)37-19-21(2)11-23(37)17-35-27/h12-19,22-23H,5-11H2,1-4H3/t22-,23?/m1/s1
InChIKey
YMTZZJOPSATRTO-WTQRLHSKSA-N
Density
1.32±0.1 g/cm3
Solubility
Soluble in DMSO
Appearance
Solid
Storage
-20°C, protect from light, stored under nitrogen; in solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Boiling Point
816.2±65.0°C at 760 mmHg
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: SG3199
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