Name: m-PEG8-COOH
Brand: BOC Sciences
Price: -- USD
Availability: MadeToOrder

Synonyms

mPEG7-propionic acid; m-PEG8-acid; 4,7,10,13,16,19,22,25-Octaoxahexacosanoic acid; mPEG7-CH2CH2COOH; 2,5,8,11,14,17,20,23-Octaoxahexacosan-26-oic acid; MPEG7-OCH2CH2COOH

IUPAC Name

3-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Canonical SMILES

COCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

InChI

InChI=1S/C18H36O10/c1-21-4-5-23-8-9-25-12-13-27-16-17-28-15-14-26-11-10-24-7-6-22-3-2-18(19)20/h2-17H2,1H3,(H,19,20)

InChIKey

JHUSQXBQANBSDC-UHFFFAOYSA-N

Density

1.111±0.06 g/cm3 (Predicted)

Solubility

Soluble in DCM, DMF, DMSO, Water

Flash Point

164.2±23.6 °C

Index Of Refraction

1.456

Vapor Pressure

0.0±2.8 mmHg at 25°C

Appearance

Pale Yellow Oily Liquid

Shipping

Room temperature

Storage

Store at 2-8°C

Boiling Point

503.0±50.0 °C at 760 mmHg

m-PEG8-COOH, a derivative of polyethylene glycol showcasing a carboxylic acid functional group, finds extensive utility across varied scientific and industrial domains. Here are four key applications of m-PEG8-COOH:

Drug Delivery: The versatile m-PEG8-COOH molecule assumes a pivotal role in enhancing drug delivery systems by boosting the solubility and stability of therapeutic compounds. Through conjugation of drugs to this molecular entity, pharmaceutical formulations achieve prolonged circulation in the bloodstream, thereby amplifying the bioavailability and efficacy of treatments.

Bioconjugation: Within the bioconjugation methodologies, m-PEG8-COOH emerges as a critical linker for binding biomolecules such as proteins or peptides to serve a myriad of biotechnological and therapeutic objectives. The reactive carboxylic group acts as a catalyst for coupling reactions, facilitating the creation of robust conjugates that enhance protein stability and mitigate immunogenic responses in clinical contexts. This utilization underscores the significance of m-PEG8-COOH in propelling advancements in bioconjugation technologies.

Surface Modification: Unleashing the potential of m-PEG8-COOH, surfaces including nanoparticles can undergo intelligent modifications to boost biocompatibility and deter nonspecific interactions. Coating surfaces with this molecular entity enables researchers to restrict protein adsorption and prevent unwanted cell adhesion, particularly advantageous in the development of cutting-edge biomedical devices and diagnostic assays. This application highlights the pivotal role played by m-PEG8-COOH in refining surface modification strategies.

Polymer Chemistry: m-PEG8-COOH emerges as a fundamental building block for crafting amphiphilic polymers tailored to a plethora of applications. These polymers have the capability to self-assemble into micelles or hydrogels, making them ideal candidates for drug delivery systems and tissue engineering endeavors. The integration of m-PEG8-COOH allows for meticulous adjustments of polymer properties, encompassing hydrophilicity and mechanical strength, underscoring its significance in fueling innovations within polymer chemistry.