Mc-MMAE - CAS 863971-24-8 Catalog number: BADC-00025

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Mc-MMAE is a protective group conjugated MMAE, MMAE inhibits tubulin polymerization so that it inhibits cell division.

Category

ADCs Cytotoxin with Linkers

Product Name

Mc-MMAE

CAS

863971-24-8

Catalog Number

BADC-00025

Molecular Formula

C49H78N6O10

Molecular Weight

911.18

Ordering Information

Catalog Number	Size	Price	Quantity
BADC-00025	1 mg	$519

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Description

Mc-MMAE is a protective group conjugated MMAE, MMAE inhibits tubulin polymerization so that it inhibits cell division.

Synonyms

Maleimidocaproyl-monomethylauristatin E; N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}- 3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide;

IUPAC Name

6-(2,5-dioxopyrrol-1-yl)-N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylhexanamide

Canonical SMILES

CC[C@]([C@@](N(C([C@](/N=C(O)/[C@](N(C(CCCCCN1C(C=CC1=O)=O)=O)C)([H])C(C)C)([H])C(C)C)=O)C)([H])[C@@](OC)([H])CC(N2CCC[C@@]2([H])[C@@](OC)([H])[C@@](/C(O)=N/[C@]([C@](O)([H])C3=CC=CC=C3)([H])C)([H])C)=O)([H])C

InChI

InChI=1S/C49H78N6O10/c1-13-32(6)44(37(64-11)29-41(59)54-28-20-23-36(54)46(65-12)33(7)47(61)50-34(8)45(60)35-21-16-14-17-22-35)53(10)49(63)42(30(2)3)51-48(62)43(31(4)5)52(9)38(56)24-18-15-19-27-55-39(57)25-26-40(55)58/h14,16-17,21-22,25-26,30-34,36-37,42-46,60H,13,15,18-20,23-24,27-29H2,1-12H3,(H,50,61)(H,51,62)/t32-,33+,34+,36-,37+,42-,43-,44-,45+,46+/m0/s1

InChIKey

UGJOTJHSQWBROP-AXJCKIDNSA-N

LogP

4.91180

PSA

195.20000

Appearance

Soild powder

Purity

≥98%

Shelf Life

≥360 days if stored properly

Shipping

Room temperature

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Historical Records: Amino-PEG4-propionic acid | Epirubicin | Mc-MMAE

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Mc-MMAE - CAS 863971-24-8 Catalog number: BADC-00025

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